Skip Navigation
ChemIDplus Lite•Browse•Advanced

Substance Name: Ethylene glycol monoethyl ether
RN: 110-80-5
UNII: IDK7C2HS09
InChIKey: ZNQVEEAIQZEUHB-UHFFFAOYSA-N

Note

  • Chemical remains on MTL because of additional testing actions (see OECD/SIDS listing)

Molecular Formula

  • C4-H10-O2

Molecular Weight

  • 90.121
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • TSCA Flag S (Substance is Identified in a Final Significant New Use Rule)
  • Tumor Data

Superlist Classification Codes

  • Reportable Quantity (RQ) = 1000 lb
  • TWA (5 ppm); skin; BEI
  • TWA 200 ppm (740 mg/m3); skin
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Regulatory Agencies (Superlist Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • 2-Ethoxyethanol
  • Ethanol, 2-ethoxy-
  • Ethylene glycol monoethyl ether

Synonyms

  • 2-Ethoxyethanol
  • 2-Ethoxyethyl alcohol
  • AI3-01236
  • Athylenglykol-monoathylather
  • Athylenglykol-monoathylather [German]
  • beta-Ethoxyethanol
  • Bikanol E 1
  • CCRIS 2294
  • Cellosolve
  • Cellosolve solvent
  • Celosolv
  • Celosolv [Czech]
  • Dowanol 8
  • Dowanol EE
  • EC 203-804-1
  • EGEE
  • EINECS 203-804-1
  • Ektasolve EE
  • Emkanol
  • Eter monoetilico del etilenglicol
  • Eter monoetilico del etilenglicol [Spanish]
  • Ethanol, 2-ethoxy-
  • Ether monoethylique de l'ethylene-glycol
  • Ether monoethylique de l'ethylene-glycol [French]
  • Ethyl cellosolve
  • Ethyl ethylene glycol
  • Ethylene glycol ethyl ether
  • Ethylene glycol monoethyl ether
  • Ethylethylene glycol
  • Etoksyetylowy alkohol
  • Etoksyetylowy alkohol [Polish]
  • Glycol monoethyl ether
  • HSDB 54
  • Hydroxy ether
  • Jeffersol EE
  • NCI-C54853
  • NSC 8837
  • Oxitol
  • Plastiazan 60
  • Poly-Solv EE
  • RCRA waste number U227
  • RCRA waste number U359
  • Solvid
  • Solvulose
  • UNII-IDK7C2HS09

Systematic Names

  • 2-Ethoxyethanol
  • Ethanol, 2-ethoxy-

Superlist Names

  • 2-Ethoxyethanol
  • Cellosolve
  • EGEE
  • Ethanol, 2-ethoxy-
  • Ethoxyethanol, 2-
  • Ethylene glycol ethyl ether
  • Ethylene glycol monoethyl ether
  • Ethylene glycol monoethyl ether [UN1171] [Flammable liquid]
  • Glycol monoethyl ether
  • RCRA waste no. U359
  • UN1171

Registry Numbers

CAS Registry Number

  • 110-80-5

FDA UNII

  • IDK7C2HS09

Other Registry Number

  • 96231-36-6

System Generated Number

  • 0000110805

Structure Descriptors

InChI

InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

InChIKey

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

Smiles

CCOCCO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LCLo inhalation 3000ppm/24H (3000ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Public Health Reports. Vol. 45, Pg. 1459, 1930.
guinea pig LD50 oral 1400mg/kg (1400mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

GASTROINTESTINAL: OTHER CHANGES		 Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
guinea pig LD50 unreported 3070mg/kg (3070mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982.
mouse LC50 inhalation 1820ppm/7H (1820ppm) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: ANALGESIA

KIDNEY, URETER, AND BLADDER: HEMATURIA		 Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 157, 1943.
mouse LD50 intraperitoneal 1707mg/kg (1707mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: CHANGES IN SPLEEN

LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA		 Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947.
mouse LD50 intravenous 3900mg/kg (3900mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)		 Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971.
mouse LD50 oral 2451mg/kg (2451mg/kg)   Kodak Company Reports. Vol. MSDS-10, Pg. 170A, 1982.
mouse LD50 unreported 5799mg/kg (5799mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982.
mouse LDLo subcutaneous 5gm/kg (5000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 42, Pg. 355, 1931.
rabbit LD50 intravenous 900mg/kg (900mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971.
rabbit LD50 oral 1275mg/kg (1275mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 78, 1988.
rabbit LD50 skin 3300mg/kg (3300mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 54, 1974.
rabbit LD50 subcutaneous 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971.
rat LC50 inhalation 2000ppm/7H (2000ppm)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 54, 1974.
rat LD50 intraperitoneal 2800mg/kg (2800mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971.
rat LD50 intravenous 2400mg/kg (2400mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 54, 1974.
rat LD50 oral 2125mg/kg (2125mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: WITHDRAWAL

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(3), Pg. 48, 1988.
rat LD50 skin 3900mg/kg (3900mg/kg)   Toxicologist. Vol. 4, Pg. 180, 1984.
rat LD50 subcutaneous 3400mg/kg (3400mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971.
rat LD50 unreported 7750mg/kg (7750mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -7.00E+01 deg C   EXP
Boiling Point 135 deg C   EXP
pKa Dissociation Constant 14.8 (none)   EXP
log P (octanol-water) -0.32 (none)   EXP
Water Solubility 1.00E+06 mg/L   EXP
Vapor Pressure 5.31 mm Hg 25 EXP
Henry's Law Constant 4.70E-07 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.54E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.