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Substance Name: Ethylene glycol monoethyl ether
RN: 110-80-5
UNII: IDK7C2HS09
InChIKey: ZNQVEEAIQZEUHB-UHFFFAOYSA-N
Note
- Chemical remains on MTL because of additional testing actions (see OECD/SIDS listing)
Molecular Formula
- C4-H10-O2
Molecular Weight
- 90.121
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Mutation Data
- Reproductive Effect
- Skin / Eye Irritant
- TSCA Flag S (Substance is Identified in a Final Significant New Use Rule)
- Tumor Data
Superlist Classification Codes
- Reportable Quantity (RQ) = 1000 lb
- TWA (5 ppm); skin; BEI
- TWA 200 ppm (740 mg/m3); skin
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Names and Synonyms
Name of Substance
- 2-Ethoxyethanol
- Ethanol, 2-ethoxy-
- Ethylene glycol monoethyl ether
Synonyms
- 2-Ethoxyethanol
- 2-Ethoxyethyl alcohol
- AI3-01236
- Athylenglykol-monoathylather
- Athylenglykol-monoathylather [German]
- beta-Ethoxyethanol
- Bikanol E 1
- CCRIS 2294
- Cellosolve
- Cellosolve solvent
- Celosolv
- Celosolv [Czech]
- Dowanol 8
- Dowanol EE
- EC 203-804-1
- EGEE
- EINECS 203-804-1
- Ektasolve EE
- Emkanol
- Eter monoetilico del etilenglicol
- Eter monoetilico del etilenglicol [Spanish]
- Ethanol, 2-ethoxy-
- Ether monoethylique de l'ethylene-glycol
- Ether monoethylique de l'ethylene-glycol [French]
- Ethyl cellosolve
- Ethyl ethylene glycol
- Ethylene glycol ethyl ether
- Ethylene glycol monoethyl ether
- Ethylethylene glycol
- Etoksyetylowy alkohol
- Etoksyetylowy alkohol [Polish]
- Glycol monoethyl ether
- HSDB 54
- Hydroxy ether
- Jeffersol EE
- NCI-C54853
- NSC 8837
- Oxitol
- Plastiazan 60
- Poly-Solv EE
- RCRA waste number U227
- RCRA waste number U359
- Solvid
- Solvulose
- UNII-IDK7C2HS09
Systematic Names
- 2-Ethoxyethanol
- Ethanol, 2-ethoxy-
Superlist Names
- 2-Ethoxyethanol
- Cellosolve
- EGEE
- Ethanol, 2-ethoxy-
- Ethoxyethanol, 2-
- Ethylene glycol ethyl ether
- Ethylene glycol monoethyl ether
- Ethylene glycol monoethyl ether [UN1171] [Flammable liquid]
- Glycol monoethyl ether
- RCRA waste no. U359
- UN1171
Registry Numbers
CAS Registry Number
- 110-80-5
FDA UNII
- IDK7C2HS09
Other Registry Number
- 96231-36-6
System Generated Number
- 0000110805
Structure Descriptors
InChI
InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3InChIKey
ZNQVEEAIQZEUHB-UHFFFAOYSA-NSmiles
CCOCCOToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LCLo | inhalation | 3000ppm/24H (3000ppm) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Public Health Reports. Vol. 45, Pg. 1459, 1930. |
guinea pig | LD50 | oral | 1400mg/kg (1400mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC KIDNEY, URETER, AND BLADDER: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES | Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941. |
guinea pig | LD50 | unreported | 3070mg/kg (3070mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982. | |
mouse | LC50 | inhalation | 1820ppm/7H (1820ppm) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ANALGESIA KIDNEY, URETER, AND BLADDER: HEMATURIA | Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 157, 1943. |
mouse | LD50 | intraperitoneal | 1707mg/kg (1707mg/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: CHANGES IN SPLEEN LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947. |
mouse | LD50 | intravenous | 3900mg/kg (3900mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971. |
mouse | LD50 | oral | 2451mg/kg (2451mg/kg) | Kodak Company Reports. Vol. MSDS-10, Pg. 170A, 1982. | |
mouse | LD50 | unreported | 5799mg/kg (5799mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982. | |
mouse | LDLo | subcutaneous | 5gm/kg (5000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 42, Pg. 355, 1931. | |
rabbit | LD50 | intravenous | 900mg/kg (900mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971. |
rabbit | LD50 | oral | 1275mg/kg (1275mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 78, 1988. | |
rabbit | LD50 | skin | 3300mg/kg (3300mg/kg) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 54, 1974. | |
rabbit | LD50 | subcutaneous | 2gm/kg (2000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971. | |
rat | LC50 | inhalation | 2000ppm/7H (2000ppm) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 54, 1974. | |
rat | LD50 | intraperitoneal | 2800mg/kg (2800mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971. | |
rat | LD50 | intravenous | 2400mg/kg (2400mg/kg) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 54, 1974. | |
rat | LD50 | oral | 2125mg/kg (2125mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: WITHDRAWAL BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(3), Pg. 48, 1988. |
rat | LD50 | skin | 3900mg/kg (3900mg/kg) | Toxicologist. Vol. 4, Pg. 180, 1984. | |
rat | LD50 | subcutaneous | 3400mg/kg (3400mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 880, 1971. | |
rat | LD50 | unreported | 7750mg/kg (7750mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -7.00E+01 | deg C | EXP | |
Boiling Point | 135 | deg C | EXP | |
pKa Dissociation Constant | 14.8 | (none) | EXP | |
log P (octanol-water) | -0.32 | (none) | EXP | |
Water Solubility | 1.00E+06 | mg/L | EXP | |
Vapor Pressure | 5.31 | mm Hg | 25 | EXP |
Henry's Law Constant | 4.70E-07 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 1.54E-11 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.