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Substance Name: Piperidine
RN: 110-89-4
UNII: 67I85E138Y
InChIKey: NQRYJNQNLNOLGT-UHFFFAOYSA-N

Molecular Formula

  • C5-H11-N

Molecular Weight

  • 85.1489
 

Classification Codes

Classification Codes

  • Calcium Channel Blockers
  • Cardiovascular Agents
  • Membrane Transport Modulators
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant

Superlist Classification Code

  • Threshold Planning Quantity (TPQ) = 1000 lb

Names and Synonyms

Name of Substance

  • Piperidine

Synonyms

  • AI3-24114
  • Azacyclohexane
  • CCRIS 967
  • Cyclopentimine
  • Cypentil
  • EC 203-813-0
  • EINECS 203-813-0
  • FEMA No. 2908
  • Hexahydropyridine
  • Hexazane
  • HSDB 114
  • Pentamethyleneimine
  • Pentamethylenimine
  • Perhydropyridine
  • Piperidin
  • Piperidin [German]
  • Piperidine
  • Pyridine, hexahydro-
  • UNII-67I85E138Y

Systematic Name

  • Piperidine

Superlist Names

  • Piperidine
  • Piperidine [UN2401] [Corrosive]
  • UN2401

Registry Numbers

CAS Registry Number

  • 110-89-4

FDA UNII

  • 67I85E138Y

System Generated Number

  • 0000110894

Structure Descriptors

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

InChIKey

NQRYJNQNLNOLGT-UHFFFAOYSA-N

Smiles

C1CCNCC1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo unreported 1750mg/kg (1750mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 595, 1948.
mammal (species unspecified) LC50 inhalation 6500mg/m3 (6500mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 90, 1975.
mammal (species unspecified) LD50 oral 22400ug/kg (22.4mg/kg)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 90, 1975.
mouse LC50 inhalation 6000mg/m3/2H (6000mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 116, 1979.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg)   Journal of Environmental Pathology and Toxicology. Vol. 4(2-3), Pg. 345, 1980.
mouse LD50 oral 30mg/kg (30mg/kg)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 116, 1979.
rabbit LD50 oral 145mg/kg (145mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.
rabbit LD50 skin 276mg/kg (276mg/kg)   American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962.
rabbit LDLo intravenous 160mg/kg (160mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
Japanese Journal of Medical Sciences, Part 4: Pharmacology. Vol. 7, Pg. 128, 1933.
rabbit LDLo subcutaneous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Japanese Journal of Medical Sciences, Part 4: Pharmacology. Vol. 7, Pg. 128, 1933.
rat LCLo inhalation 4000ppm/4H (4000ppm)   American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962.
rat LD50 oral 400mg/kg (400mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(2), Pg. 29, 1974.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.10E+01 deg C   EXP
Boiling Point 106.2 deg C   EXP
pKa Dissociation Constant 11.28 (none) 20 EXP
log P (octanol-water) 0.84 (none)   EXP
Water Solubility 1.00E+06 mg/L 20 EXP
Vapor Pressure 32.1 mm Hg 25 EXP
Henry's Law Constant 4.45E-06 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 8.86E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.