Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Vasopressin
RN: 11000-17-2
UNII: Y87Y826H08
InChIKey: JLTCWSBVQSZVLT-UHFFFAOYSA-N

Note

  • Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.

Molecular Formula

  • Unspecified

Molecular Weight

  • 2140.475
 

Classification Codes

  • Antidiuretic Agents
  • Cardiovascular Agents
  • Coagulants
  • Hematologic Agents
  • Hemostatics
  • Natriuretic Agents
  • Vasoconstrictor Agents

Names and Synonyms

Name of Substance

  • Vasopressin
  • Vasopressins

MeSH Heading

  • Vasopressins

Synonyms

  • ADH
  • ADH (hormone)
  • Antidiuretic hormone
  • beta-Hypophamine
  • EINECS 234-236-2
  • HSDB 3412
  • Intertocin
  • Inyectable de vasopresina
  • Inyectable de vasopresina [INN-Spanish]
  • Leiormone
  • Pitressin
  • Pituitrin
  • Pituitrin P
  • Solute injectable de vasopressine
  • Solute injectable de vasopressine [INN-French]
  • Tonephin
  • UNII-Y87Y826H08
  • Vasophysin
  • Vasopressin
  • Vasopressin injection
  • Vasopressin, unspecified
  • Vasopressina
  • Vasopressina [DCIT]
  • Vasopressine
  • Vasopressini injectio
  • Vasopressini injectio [INN-Latin]
  • Vasopressins
  • Vasopressinum
  • Vasostrict

Systematic Name

  • Vasopressin

Registry Numbers

CAS Registry Number

  • 11000-17-2

FDA UNII

  • Y87Y826H08

Other Registry Numbers

  • 11034-16-5
  • 12678-42-1

System Generated Number

  • 0011000172

Structure Descriptors

InChI

1S/C46H65N15O12S2.C46H65N13O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25;47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53);1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)

InChIKey

JLTCWSBVQSZVLT-UHFFFAOYSA-N

Smiles

NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(N)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(Cc4ccccc4)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)N2)C(=O)NCC(=O)N.NC5CSSCC(NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(Cc6ccccc6)NC(=O)C(Cc7ccc(O)cc7)NC5=O)C(=O)N8CCCC8C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 220iu/kg (220iu/kg)   Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 415, 1963.