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Substance Name: Virginiamycin [USAN:INN:BAN]
RN: 11006-76-1
UNII: C49WS9N75L
InChIKey: MVTQIFVKRXBCHS-SMMNFGSLSA-N
Note
- A cyclic polypeptide antibiotic complex from Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. It consists of 2 major components, VIRGINIAMYCIN FACTOR M1 and virginiamycin Factor S1. It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.
Molecular Formula
- Unspecified
Molecular Weight
- 1349.4976
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibacterial
- Drug / Therapeutic Agent
- Enzyme Inhibitors
- Food Additive (Veterinary)
- Natural Product
- Protein Synthesis Inhibitors
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Names and Synonyms
Name of Substance
- Virginiamycin
- Virginiamycin [USAN:INN:BAN]
MeSH Heading
- Virginiamycin
Synonyms
- A mixture of two principal antibiotic components, virginiamycin M1 (Factor M1) and virginiamycin S1 (Factor S). Virginiamycin
- Antibiotic No. 899
- Antibiotic produced by Streptomyces virginiae; a mixture of two principal antibiotic components, virginiamycin M1 (Factor M1) and virginiamycin S1 (Factor S)
- EINECS 234-244-6
- Eskalin
- Eskalin 500
- Eskalin V
- HSDB 7033
- Micamicina
- Micamicina [INN-Spanish]
- Mikamycin
- Mikamycin [INN:BAN:DCF]
- Mikamycine
- Mikamycine [INN-French]
- Mikamycinum
- Mikamycinum [INN-Latin]
- Ostreogricina
- Ostreogricina [INN-Spanish]
- Ostreogrycin
- Ostreogrycin [INN:BAN]
- Ostreogrycine
- Ostreogrycine [INN-French]
- Ostreogrycinum
- Ostreogrycinum [INN-Latin]
- Patricin
- Pristinamicina
- Pristinamicina [INN-Spanish]
- Pristinamycin
- Pristinamycin [INN:BAN:DCF]
- Pristinamycine
- Pristinamycine [INN-French]
- Pristinamycinum
- Pristinamycinum [INN-Latin]
- Pyostacine
- RP 7293
- RP7293
- SK&F 7988
- SKF 7988
- Stafac
- Stafac 20
- Stafac 50
- Stafac 500
- Staphylomycin
- Stapyocine
- Streptogramin
- UNII-C49WS9N75L
- V-MAX 50
- Vernamycin
- Virgimycin
- Virginiamicina
- Virginiamicina [INN-Spanish]
- Virginiamycin
- Virginiamycina
- Virginiamycina [INN-Spanish]
- Virginiamycine
- Virginiamycine [INN-French]
- Virginiamycinum
- Virginiamycinum [INN-Latin]
Systematic Names
- Antibiotic produced by Streptomyces mitakaensis, or the same substance produced by any other means
- Antibiotic produced by Streptomyces pristina spiralis, or the same substance produced by any other means
- Antibiotic produced by Streptomyces virginiae
- Antibiotic substances derived from cultures of Streptomyces osteogriseus, or the same substance produced by any other means
- Virginiamycin
Registry Numbers
CAS Registry Number
- 11006-76-1
FDA UNII
- C49WS9N75L
Other Registry Numbers
- 11006-28-3
- 11006-49-8
- 11100-46-2
- 11113-94-3
- 11132-90-4
- 12620-11-0
- 1401-44-1
- 1407-07-4
- 63496-49-1
- 63496-50-4
- 8065-94-9
System Generated Number
- 0011006761
Structure Descriptors
InChI
InChI=1S/C43H49N7O10.C28H35N3O7/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36;1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53);5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b;7-5+,10-9+,18-13+/t25-,29-,30+,31+,32+,34+,35+;19-,20-,26-/m11/s1InChIKey
MVTQIFVKRXBCHS-SMMNFGSLSA-NSmiles
CC[C@H]1NC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 450mg/kg (450mg/kg) | Antibiotics Annual. Vol. 1, Pg. 171, 1953/1954. | |
mouse | LD50 | oral | 2100mg/kg (2100mg/kg) | "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 383, 1978. | |
mouse | LD50 | subcutaneous | 2500mg/kg (2500mg/kg) | "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 383, 1978. |