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Substance Name: Bambermycins [USAN]
RN: 11015-37-5
UNII: PP922A42V2
InChIKey: FUIOWSNNCWZETH-NAMXWVJMSA-N

Note

  • Antibiotic complex obtained from Streptomyces bambergiensis containing mainly Moenomycins A and C. They are used as feed additives and growth promoters for poultry, swine, and cattle.

Molecular Formula

  • Unspecified

Molecular Weight

  • 1597.6
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibacterial
  • Drug / Therapeutic Agent
  • Natural Product
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Names and Synonyms

Name of Substance

  • Bambermycin [INN]
  • Bambermycins
  • Bambermycins [USAN]
  • Moenomycin
  • Moenomycin A

MeSH Heading

  • Bambermycins

Synonyms

  • Antibiotic complex, containing mainly moenomycin A and C, obtained from cultures of Streptomyces bambergiensis, or the same substance obtained by any other means. Bambermycin
  • Bambermicina
  • Bambermicina [INN-Spanish]
  • Bambermycin
  • Bambermycine
  • Bambermycine [INN-French]
  • Bambermycins
  • Bambermycinum
  • Bambermycinum [INN-Latin]
  • EINECS 234-246-7
  • Flavofosfolipol
  • Flavomycin
  • Flavophospholipol
  • Gainpro
  • Menomycin
  • Moenomycin
  • Moenomycin A
  • UNII-PP922A42V2

Systematic Names

  • Antibiotic complex, containing mainly moenomycin A and C, obtained from cultures of Streptomyces bambergiensis, or the same substance obtained by any other means
  • Bambermycin
  • Moenomycin

Registry Numbers

CAS Registry Number

  • 11015-37-5

FDA UNII

  • PP922A42V2

Other Registry Numbers

  • 11103-61-0
  • 39324-84-0
  • 51331-18-1

System Generated Number

  • 0011015375

Structure Descriptors

InChI

1S/C70H109N4O35P/c1-31(2)16-14-18-33(4)20-21-34(5)24-26-69(9,10)25-13-12-17-32(3)19-15-27-97-62(92)40(80)29-99-110(95,96)109-67-57(58(108-68(71)93)70(11,94)59(107-67)61(90)91)106-64-45(73-37(8)77)48(83)55(42(102-64)30-98-65-52(87)49(84)46(81)41(28-75)101-65)104-63-44(72-36(7)76)47(82)54(35(6)100-63)103-66-53(88)50(85)51(86)56(105-66)60(89)74-43-38(78)22-23-39(43)79/h13,16,19-20,25,35,40-42,44-59,63-67,75,78,80-88,94H,5,12,14-15,17-18,21-24,26-30H2,1-4,6-11H3,(H2,71,93)(H,72,76)(H,73,77)(H,74,89)(H,90,91)(H,95,96)/b25-13+,32-19+,33-20+/t35-,40-,41-,42-,44-,45-,46-,47-,48-,49+,50+,51-,52-,53-,54-,55-,56+,57-,58-,59-,63+,64+,65-,66-,67-,70+/m1/s1

InChIKey

FUIOWSNNCWZETH-NAMXWVJMSA-N

Smiles

O([C@H]1[C@H](O[C@H](C(O)=O)[C@@]([C@@H]1OC(N)=O)(C)O)O[P@@](OC[C@H](C(OCC\C=C(\CC\C=C\C(CCC(C\C=C(\CC\C=C(\C)C)C)=C)(C)C)C)=O)O)(O)=O)[C@H]1[C@@H]([C@H]([C@H](O[C@H]2[C@@H]([C@H]([C@H](O[C@@H]3O[C@H](C(NC=4C(CCC4O)=O)=O)[C@H](O)[C@@H]([C@H]3O)O)[C@H](O2)C)O)NC(C)=O)[C@H](O1)CO[C@@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)O)CO)O)NC(C)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 600mg/kg (600mg/kg) AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)"

BEHAVIORAL: WAKEFULNESS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Antimicrobial Agents and Chemotherapy Vol. -, Pg. 743, 1965.
mouse LD50 intravenous 200mg/kg (200mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 740, 1978.
mouse LD50 subcutaneous 500mg/kg (500mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 740, 1978.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) -11.72 (none)   EST
Atmospheric OH Rate Constant 6.92E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.