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Substance Name: Concanavalin A
RN: 11028-71-0

Note

  • A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.
 

Classification Codes

  • Mitogens
  • Mitosis Modulators
  • Mutation Data
  • Reproductive Effect
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Links to Resources

Names and Synonyms

Name of Substance

  • Concanavalin A

MeSH Heading

  • Concanavalin A

Synonyms

  • CON A
  • Concanavalin A
  • Concanavaline A
  • EINECS 234-258-2
  • NSC 143504
  • Ricin-toxin con A
  • RTECS GX8792000

Systematic Name

  • Concanavalin A

Registry Numbers

CAS Registry Number

  • 11028-71-0

System Generated Number

  • 0011028710

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 41500ug/kg (41.5mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 intravenous 50mg/kg (50mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 759, 1980.
rabbit LDLo intravenous 5385ug/kg (5.385mg/kg)   Journal of Bacteriology. Vol. 32, Pg. 227, 1936.