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Substance Name: Heliomycin [INN]
RN: 11029-70-2
UNII: 7N3A092A5X
InChIKey: ABLACSIRCKEUOB-UHFFFAOYSA-N

Note

  • Russian drug; antibiotic with antiviral properties isolated from Actinomyces flavochromogenes var. heliomycini.

Molecular Formula

  • C23-H18-O6

Molecular Weight

  • 376.3624
 

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product
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Names and Synonyms

Name of Substance

  • Heliomycin
  • Heliomycin [INN]

Synonyms

  • Heliomicina
  • Heliomicina [INN-Spanish]
  • Heliomycin
  • Heliomycine
  • Heliomycine [INN-French]
  • Heliomycinum
  • Heliomycinum [INN-Latin]
  • UNII-7N3A092A5X

Systematic Names

  • Antibiotic obtained from cultures of Actinomyces flavochromogenes var. heliomycini or the same substance obtained by any other means
  • Geliomitsin
  • Heliomycin

Registry Numbers

CAS Registry Number

  • 11029-70-2

FDA UNII

  • 7N3A092A5X

System Generated Number

  • 0011029702

Structure Descriptors

InChI

1S/C22H16O6/c1-7-4-9(23)15-18-13(7)10(24)5-8-14(18)19-16(20(15)27)11(25)6-12(26)17(19)21(28)22(8,2)3/h4-6,23-26H,1-3H3

InChIKey

ABLACSIRCKEUOB-UHFFFAOYSA-N

Smiles

Cc1cc(c2c3c1c(cc4c3-c5c(c(cc(c5C(=O)C4(C)C)O)O)C2=O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 25mg/kg (25mg/kg)   "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 326, 1967.
mouse LD50 intravenous 40400ug/kg (40.4mg/kg)   Antibiotiki. Vol. 5(1), Pg. 107, 1960.
rabbit LDLo intravenous 6mg/kg (6mg/kg)   Antibiotiki. Vol. 5(1), Pg. 107, 1960.