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Substance Name: Cholestyramine resin [USP]
RN: 11041-12-6
UNII: 4B33BGI082

Note

  • A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.

Molecular Formula

  • Unspecified

Molecular Weight

  • 341.9232
 

Classification Codes

  • Anion Exchange Resins
  • Anticholesteremic Agents
  • Antihyperlipidemic
  • Antimetabolites
  • Human Data
  • Hypolipidemic Agents
  • Ion Exchange Resins
  • Ion-Exchange Resin (Bile Salts)
  • Lipid Regulating Agents
  • Reproductive Effect
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
  • Tumor Data

Names and Synonyms

Name of Substance

  • Cholestyramine
  • Cholestyramine resin
  • Cholestyramine resin [USP]
  • Colestyramine [INN]

MeSH Heading

  • Cholestyramine resin

Synonyms

  • CCRIS 725
  • Cholestyramine
  • Cholestyramine chloride
  • Cholestyramine Light
  • Cholestyramine resin
  • Cholybar
  • Colestiramina
  • Colestiramina [INN-Spanish]
  • Colestyramin
  • Colestyramine
  • Colestyraminum
  • Colestyraminum [INN-Latin]
  • Cuemid
  • Duolite AP-143 Resin
  • Duolite AP143 Resin
  • EINECS 234-270-8
  • HSDB 7219
  • Locholest
  • Locholest Light
  • Polystyrene benzyltrimethylaminonium chloride
  • Prevalite
  • Quantalan
  • Questran
  • Questran Light
  • UNII-4B33BGI082

Systematic Name

  • Cholestyramine

Registry Numbers

CAS Registry Number

  • 11041-12-6

FDA UNII

  • 4B33BGI082

Other Registry Numbers

  • 58391-37-0
  • 9007-26-5

System Generated Number

  • 0011041126

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 46gm/kg/39W-I (46000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BLOOD: HEMORRHAGE
Canadian Medical Association Journal. Vol. 134, Pg. 609, 1986.
infant TDLo oral 4gm/kg/2D-I (4000mg/kg)   American Journal of Diseases of Children. Vol. 141, Pg. 479, 1987.
infant TDLo unreported 42gm/kg/7W-I (42000mg/kg) BLOOD: EOSINOPHILIA Clinical Pediatrics Vol. 20, Pg. 675, 1981.
mouse LD50 intraperitoneal > 4gm/kg (4000mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.
mouse LD50 oral > 7500mg/kg (7500mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.
mouse LD50 subcutaneous > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.
rabbit LD50 oral > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.
rat LD50 intraperitoneal > 1600mg/kg (1600mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.
rat LD50 oral > 4gm/kg (4000mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.
rat LD50 subcutaneous > 1200mg/kg (1200mg/kg)   Drugs in Japan Vol. -, Pg. 412, 1990.