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Substance Name: Mitomalcin [USAN:INN]
RN: 11043-99-5

Note

  • Isolated from Streptomyces malayensis; may be similar in structure to neocarzinostatin.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Antineoplastic
  • Drug / Therapeutic Agent
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Links to Resources

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Names and Synonyms

Name of Substance

  • Mitomalcin
  • Mitomalcin [USAN:INN]

Synonyms

  • Amritamycin
  • B 2992
  • B 2992 Active principle
  • Mitomalcin
  • Mitomalcina
  • Mitomalcina [INN-Spanish]
  • Mitomalcine
  • Mitomalcine [INN-French]
  • Mitomalcinum
  • Mitomalcinum [INN-Latin]
  • NSC B-2992
  • NSC-113,233
  • NSC-113233

Systematic Name

  • Mitomalcin

Registry Numbers

CAS Registry Number

  • 11043-99-5

System Generated Number

  • 0011043995

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 7521ug/kg (7.521mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 intraperitoneal 9893ug/kg (9.893mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 intravenous 4952ug/kg (4.952mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 subcutaneous 7053ug/kg (7.053mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,