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Substance Name: Kidamycin
RN: 11072-82-5
InChIKey: MFTJRTUKCOVIMD-BOPFTXTBSA-N

Note

  • Obtained from Streptomyces phaeoverticillatus strains; interferes with RNA synthesis.

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product

Molecular Formula

  • C39-H48-N2-O9

Molecular Weight

  • 688.8132
 
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Names and Synonyms

Name of Substance

  • Kidamycin

Synonyms

  • 289-F
  • Iyomycin-F
  • Kidamycin
  • NSC 143094
  • NSC 295565

Systematic Name

  • 4H-Anthra(1,2-b)pyran-4,7,12-trione, 11-hydroxy-5-methyl-2-(1-methyl-1-propenyl)-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D-arabino-hexopyranosyl)-10-(2,3,6-trideoxy-3-(dimethylamino)-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-, (E)-

Registry Numbers

CAS Registry Number

  • 11072-82-5

System Generated Number

  • 0011072825

Structure Descriptors

InChI

1S/C39H48N2O9/c1-11-17(2)26-15-25(42)29-18(3)12-23-31(37(29)50-26)36(46)32-30(35(23)45)21(27-14-24(40(7)8)33(43)19(4)48-27)13-22(34(32)44)28-16-39(6,41(9)10)38(47)20(5)49-28/h11-13,15,19-20,24,27-28,33,38,43-44,47H,14,16H2,1-10H3/b17-11-

InChIKey

MFTJRTUKCOVIMD-BOPFTXTBSA-N

Smiles

C/C=C(/C)\c1cc(=O)c2c(cc3c(c2o1)C(=O)c4c(c(cc(c4O)C5CC(C(C(O5)C)O)(C)N(C)C)C6CC(C(C(O6)C)O)N(C)C)C3=O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 18mg/kg (18mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1452, 1978.
mouse LD50 intravenous 14mg/kg (14mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1452, 1978.