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Substance Name: Lividomycin
RN: 11111-23-2
InChIKey: DBLVDAUGBTYDFR-SWMBIRFSSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Weight

  • 761.7705
 
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Names and Synonyms

Synonyms

  • Lividomycin
  • Livodymycin
  • LVM

Systematic Name

  • Lividomycin

Registry Numbers

CAS Registry Number

  • 11111-23-2

System Generated Number

  • 0011111232

Structure Descriptors

InChI

1S/C29H55N5O18/c30-3-11-23(51-28-20(43)19(42)17(40)13(5-36)47-28)18(41)15(34)27(45-11)50-24-14(6-37)48-29(21(24)44)52-25-16(39)7(31)1-8(32)22(25)49-26-9(33)2-10(38)12(4-35)46-26/h7-29,35-44H,1-6,30-34H2/t7-,8+,9-,10+,11+,12-,13-,14-,15-,16+,17-,18-,19+,20+,21-,22-,23-,24-,25-,26-,27-,28-,29+/m1/s1

InChIKey

DBLVDAUGBTYDFR-SWMBIRFSSA-N

Smiles

C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H](C[C@@H]([C@H](O2)CO)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O[C@@H]5[C@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)O)N)O)O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 1348mg/kg (1348mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
mouse LD50 intravenous 225mg/kg (225mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: MUSCLE WEAKNESS

SENSE ORGANS AND SPECIAL SENSES: "RETINAL CHANGES (PIGMENTARY DEPOSITIONS, RETINITIS, OTHER): EYE"
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
mouse LD50 subcutaneous 1249mg/kg (1249mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
rat LD50 intramuscular 1750mg/kg (1750mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
rat LD50 intravenous 365mg/kg (365mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: MUSCLE WEAKNESS
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
rat LD50 oral > 10gm/kg (10000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.
rat LD50 subcutaneous 1819mg/kg (1819mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972.