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Substance Name: Mepartricin [USAN:INN:BAN]
RN: 11121-32-7
UNII: B7FBW3Y74G
InChIKey: GTBKZCQTNWWEIB-PBSBGHGNSA-N
Note
- Polyene macrolide antibiotic with unknown composition. It is obtained from Streptomyces aureofaciens. It is used as an antifungal agent, an antiprotozoal agent, and in the treatment of BENIGN PROSTATIC HYPERTROPHY.
Molecular Formula
- Unspecified
Molecular Weight
- 1141.3502
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antifungal
- Antifungal Agents
- Antiparasitic Agents
- Antiprotozoal
- Antiprotozoal Agents
- Drug / Therapeutic Agent
- Natural Product
- Urological Agents
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Names and Synonyms
Name of Substance
- Mepartricin
- Mepartricin [USAN:INN:BAN]
MeSH Heading
- Mepartricin
Synonyms
- Ipertrofan
- Mepartricin
- Mepartricina
- Mepartricina [INN-Spanish]
- Mepartricine
- Mepartricine [INN-French]
- Mepartricinum
- Mepartricinum [INN-Latin]
- Methylpartricin
- Orofungin
- SN 654
- SN654
- Spa-S-160
- Tricandil
- Tricangine
- UNII-B7FBW3Y74G
Systematic Names
- Partricin, methyl ester
- Partricin, methyl-
Registry Numbers
CAS Registry Number
- 11121-32-7
FDA UNII
- B7FBW3Y74G
Other Registry Number
- 12795-77-6
System Generated Number
- 0011121327
Structure Descriptors
InChI
InChI=1S/C60H88N2O19/c1-36-19-17-15-13-11-9-7-6-8-10-12-14-16-18-20-50(79-59-55(74)53(61)54(73)38(3)78-59)57-52(58(75)77-5)49(71)35-60(76,81-57)34-47(69)31-45(67)29-43(65)27-42(64)28-44(66)30-46(68)33-51(72)80-56(36)37(2)21-26-41(63)32-48(70)39-22-24-40(62-4)25-23-39/h6-19,22-25,36-38,41-43,45-47,49-50,52-57,59,62-65,67-69,71,73-74,76H,20-21,26-35,61H2,1-5H3/b7-6-,10-8+,11-9-,14-12+,15-13+,18-16+,19-17+/t36?,37?,38-,41?,42?,43?,45?,46?,47?,49?,50?,52?,53+,54-,55+,56?,57?,59?,60?/m1/s1InChIKey
GTBKZCQTNWWEIB-PBSBGHGNSA-NSmiles
CNc1ccc(cc1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 11100ug/kg (11.1mg/kg) | Journal of Pharmaceutical Sciences. Vol. 65, Pg. 905, 1976. | |
mouse | LD50 | intravenous | 4300ug/kg (4.3mg/kg) | Journal of Pharmaceutical Sciences. Vol. 65, Pg. 905, 1976. | |
mouse | LD50 | oral | > 2gm/kg (2000mg/kg) | Farmaco, Edizione Scientifica. Vol. 33, Pg. 21, 1978. |