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Substance Name: Enloplatin [USAN:INN]
RN: 111523-41-2
UNII: C7HT2IO79H
InChIKey: NAFFDQVVNWTDJD-UHFFFAOYSA-L

Classification Codes

  • Antineoplastic
  • Drug / Therapeutic Agent

Molecular Formula

  • C13-H22-N2-O5-Pt

Molecular Weight

  • 479.39
 
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Names and Synonyms

Name of Substance

  • Enloplatin
  • Enloplatin [USAN:INN]

Synonyms

  • cis-(1,1-Cyclobutanedicarboxylato)(tetrahydro-4H-pyran-4,4-bis(methylamine))platinum
  • CL 287,110
  • CL 287110
  • Enloplatin
  • Enloplatine
  • Enloplatine [INN-French]
  • Enloplatino
  • Enloplatino [INN-Spanish]
  • Enloplatinum
  • Enloplatinum [INN-Latin]
  • Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyran-4,4-dimethanamine-N,N')-, (SP-4-2)-
  • UNII-C7HT2IO79H

Systematic Name

  • Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyran-4,4-dimethanamine-N,N')-, (SP-4-2)-

Registry Numbers

CAS Registry Number

  • 111523-41-2

FDA UNII

  • C7HT2IO79H

System Generated Number

  • 0111523412

Structure Descriptors

InChI

1S/C7H14N2O.C6H8O4.Pt/c8-5-7(6-9)1-3-10-4-2-7;7-4(8)6(5(9)10)2-1-3-6;/h8-9H,1-6H2;1-3H2,(H,7,8)(H,9,10);/q-2;;+4/p-2

InChIKey

NAFFDQVVNWTDJD-UHFFFAOYSA-L

Smiles

C1CC2(C1)C(=O)[O-][Pt+2]3(NCC4(CCOCC4)CN3)[O-]C2=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 75mg/kg (75mg/kg)   Drugs of the Future. Vol. 17, Pg. 459, 1992.
rat LD50 intravenous 200mg/kg (200mg/kg)   Drugs of the Future. Vol. 17, Pg. 459, 1992.