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Substance Name: Prinoxodan [USAN:INN]
RN: 111786-07-3
UNII: W4VMH2E80M
InChIKey: SUCNEHPNQBBVHQ-UHFFFAOYSA-N

Classification Codes

  • Cardiotonic
  • Drug / Therapeutic Agent

Molecular Formula

  • C13-H14-N4-O2

Molecular Weight

  • 258.28
 
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Names and Synonyms

Name of Substance

  • Prinoxodan
  • Prinoxodan [USAN:INN]

Synonyms

  • 3,4-Dihydro-3-methyl-6-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2(1H)-quinazolinone
  • Prinoxodan
  • Prinoxodano
  • Prinoxodano [INN-Spanish]
  • Prinoxodanum
  • Prinoxodanum [INN-Latin]
  • RGW 2938
  • RGW-2938
  • UNII-W4VMH2E80M

Systematic Name

  • 2(1H)-Quinazolinone, 3,4-dihydro-3-methyl-6-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-

Registry Numbers

CAS Registry Number

  • 111786-07-3

FDA UNII

  • W4VMH2E80M

System Generated Number

  • 0111786073

Structure Descriptors

InChI

1S/C13H14N4O2/c1-17-7-9-6-8(2-3-10(9)14-13(17)19)11-4-5-12(18)16-15-11/h2-3,6H,4-5,7H2,1H3,(H,14,19)(H,16,18)

InChIKey

SUCNEHPNQBBVHQ-UHFFFAOYSA-N

Smiles

c12c(ccc(c1)C=1CCC(=O)NN1)NC(=O)N(C2)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intraperitoneal > 2gm/kg (2000mg/kg)   Cardiovascular Drug Reviews. Vol. 8, Pg. 323, 1990.
mouse LD intravenous > 2mg/kg (2mg/kg)   Cardiovascular Drug Reviews. Vol. 8, Pg. 323, 1990.
mouse LD oral > 5gm/kg (5000mg/kg)   Cardiovascular Drug Reviews. Vol. 8, Pg. 323, 1990.
rat LD intraperitoneal > 2gm/kg (2000mg/kg)   Cardiovascular Drug Reviews. Vol. 8, Pg. 323, 1990.
rat LD intravenous > 2mg/kg (2mg/kg)   Cardiovascular Drug Reviews. Vol. 8, Pg. 323, 1990.
rat LD oral > 5gm/kg (5000mg/kg)   Cardiovascular Drug Reviews. Vol. 8, Pg. 323, 1990.