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Substance Name: Quetiapine fumarate [USAN]
RN: 111974-72-2
UNII: 2S3PL1B6UJ
InChIKey: ZTHJULTYCAQOIJ-WXXKFALUSA-N

Note

  • A dibenzothiazepine and ANTIPSYCHOTIC AGENT that targets the SEROTONIN 5-HT2 RECEPTOR; HISTAMINE H1 RECEPTOR, adrenergic alpha1 and alpha2 receptors, as well as the DOPAMINE D1 RECEPTOR and DOPAMINE D2 RECEPTOR. It is used in the treatment of SCHIZOPHRENIA; BIPOLAR DISORDER and DEPRESSIVE DISORDER.

Molecular Formula

  • (C21-H25-N3-O2-S)2.C4-H4-O4

Molecular Weight

  • 883.0986
 

Classification Codes

  • Antipsychotic
  • Antipsychotic Agents
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Psychotropic Drugs
  • Tranquilizing Agents

Names and Synonyms

Name of Substance

  • Quetiapine fumarate [USAN]

MeSH Heading

  • Quetiapine Fumarate

Synonyms

  • 2-(2-(4-Dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol fumarate (2:1) (salt)
  • 2-(2-(4-Dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
  • Ethanol, 2-(2-(4-dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)-, (E)-2-butenedioate (2:1) (salt)
  • FK949E
  • ICI 204,636
  • ICI 204636
  • Quetiapine fumarate
  • Seroquel
  • Seroquel XR
  • UNII-2S3PL1B6UJ
  • ZD5077
  • ZM 204,636
  • ZM 204636

Systematic Name

  • Ethanol, 2-(2-(4-dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)-, (E)-2-butenedioate (2:1) (salt)

Registry Numbers

CAS Registry Number

  • 111974-72-2

FDA UNII

  • 2S3PL1B6UJ

System Generated Number

  • 0111974722

Molecular Formulas

Molecular Formula

  • (C21-H25-N3-O2-S)2.C4-H4-O4

Molecular Formula Fragments

  • C21-H25-N3-O2-S
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChIKey

ZTHJULTYCAQOIJ-WXXKFALUSA-N

Smiles

c1ccc2c(c1)C(=Nc3ccccc3S2)N4CCN(CC4)CCOCCO.c1ccc2c(c1)C(=Nc3ccccc3S2)N4CCN(CC4)CCOCCO.C(=C/C(=O)O)\C(=O)O