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Substance Name: Triethylene glycol
RN: 112-27-6
UNII: 3P5SU53360
InChIKey: ZIBGPFATKBEMQZ-UHFFFAOYSA-N

Classification Codes

  • Agricultural Chemical
  • Germicide, Bactericide, Disinfectant
  • Human Data
  • Reproductive Effect
  • Skin / Eye Irritant

Molecular Formula

  • C6-H14-O4

Molecular Weight

  • 150.173
 

Names and Synonyms

Name of Substance

  • 2,2'-(1,2-Ethanediylbis(oxy))bisethanol
  • Triethylene glycol

Synonyms

  • 1,2-Bis(2-hydroxyethoxy)ethane
  • 2,2'-(1,2-Ethanediylbis(oxy))bisethanol
  • 2,2'-Ethylenedioxybis(ethanol)
  • 2,2'-Ethylenedioxydiethanol
  • 2,2'-Ethylenedioxyethanol
  • 3,6-Dioxaoctane-1,8-diol
  • 4-01-00-02400 (Beilstein Handbook Reference)
  • AI3-01453
  • Bis(2-hydroxyethoxyethane)
  • BRN 0969357
  • Caswell No. 888
  • CCRIS 8926
  • Di-beta-hydroxyethoxyethane
  • EC 203-953-2
  • EINECS 203-953-2
  • EPA Pesticide Chemical Code 083501
  • Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-
  • Ethanol, 2,2'-(ethylenedioxy)di-
  • Ethylene glycol dihydroxydiethyl ether
  • Ethylene glycol-bis-(2-hydroxyethyl ether)
  • Glycol bis(hydroxyethyl) ether
  • HSDB 898
  • NSC 60758
  • TEG
  • Triethylene glycol
  • Triethyleneglycol
  • Triethylenglykol
  • Triethylenglykol [Czech]
  • Trigen
  • Triglycol
  • UNII-3P5SU53360

Systematic Names

  • 2,2'-(Ethylenedioxy)diethanol
  • Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-
  • Triethylene glycol

Superlist Names

  • Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-
  • Triethylene glycol

Registry Numbers

CAS Registry Number

  • 112-27-6

FDA UNII

  • 3P5SU53360

Other Registry Numbers

  • 118662-30-9
  • 121202-29-7
  • 676-18-6
  • 939972-01-7

System Generated Number

  • 0000112276

Structure Descriptors

InChI

1S/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2

InChIKey

ZIBGPFATKBEMQZ-UHFFFAOYSA-N

Smiles

C(COCCO)OCCO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 4500mg/kg (4500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
guinea pig LD50 intravenous 10600mg/kg (10600mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
guinea pig LD50 oral 7900mg/kg (7900mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
human LDLo oral 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 17, Pg. 913, 1979.
mammal (species unspecified) LD50 oral 8150mg/kg (8150mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse LD50 intraperitoneal 8141mg/kg (8141mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI

BLOOD: CHANGES IN SPLEEN
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947.
mouse LD50 intravenous 6500mg/kg (6500mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.
mouse LD50 subcutaneous 8750mg/kg (8750mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.
mouse LDLo oral 18500mg/kg (18500mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1186, 1966.
rabbit LD50 intravenous 1900mg/kg (1900mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
rabbit LD50 oral 8400mg/kg (8400mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
rabbit LD50 skin > 20mL/kg (20mL/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
rat LD50 intravenous 11700mg/kg (11700mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
rat LD50 oral 17gm/kg (17000mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
rat LDLo intramuscular 8400mg/kg (8400mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 5, 1940.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -7.00E+00 deg C   EXP
Boiling Point 285 deg C   EXP
log P (octanol-water) -1.980 (none)   EST
Water Solubility 1.00E+06 mg/L   EXP
Vapor Pressure 0.00132 mm Hg 25 EXP
Henry's Law Constant 2.61E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 3.64E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.