|
|
Substance Name: Ligustrazine
RN: 1124-11-4
UNII: V80F4IA5XG
InChIKey: FINHMKGKINIASC-UHFFFAOYSA-N
Note
- Found in Ligusticum chuanxiong.
Classification Codes
- Cardiovascular Agents
- Vasodilator Agents
Molecular Formula
- C8-H12-N2
Molecular Weight
- 136.197
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Results Name
- Ligustrazine
Name of Substance
- Tetramethylpyrazine
Synonyms
- 2,3,5,6-Tetramethyl pyrazine
- 2,3,5,6-Tetramethylpyrazine
- 2,3,5,6-Tetramethylpyrazine (natural)
- Bs factor
- EINECS 214-391-2
- FEMA No. 3237
- Ligustrazine
- Liqustrazine
- NSC 36080
- NSC 46451
- Pyrazine, tetramethyl-
- Tetramethylpyrazin
- Tetramethylpyrazine
- Tetrapyrazine
- UNII-V80F4IA5XG
Systematic Names
- 2,3,5,6-Tetramethylpyrazine
- Pyrazine, 2,3,5,6-tetramethyl-
- Pyrazine, tetramethyl-
Superlist Name
- Tetramethylpyrazine
Registry Numbers
CAS Registry Number
- 1124-11-4
FDA UNII
- V80F4IA5XG
Other Registry Numbers
- 87396-75-6
- 93615-56-6
Related Registry Number
- 76494-51-4 (hydrochloride)
System Generated Number
- 0001124114
Structure Descriptors
InChI
1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3InChIKey
FINHMKGKINIASC-UHFFFAOYSA-NSmiles
c1(c(nc(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 800ug/kg (0.8mg/kg) | International Journal of Crude Drug Research. Vol. 23, Pg. 119, 1985. | |
mouse | LD50 | intravenous | 239mg/kg (239mg/kg) | Chinese Medical Journal Vol. 4, Pg. 319, 1978. | |
rat | LD50 | oral | 1910mg/kg (1910mg/kg) | Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 84-86 | deg C | EXP | |
Boiling Point | 190 | deg C | EXP | |
pKa Dissociation Constant | 3.55 | (none) | 27 | EXP |
log P (octanol-water) | 1.28 | (none) | EXP | |
Water Solubility | 7010 | mg/L | 25 | EST |
Vapor Pressure | 0.169 | mm Hg | 25 | EST |
Henry's Law Constant | 4.33E-06 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 2.90E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.