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Substance Name: Amifostine [USAN:USP:INN:BAN]
RN: 112901-68-5
UNII: M487QF2F4V
InChIKey: TXQPXJKRNHJWAX-UHFFFAOYSA-N

Note

  • A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

Molecular Formula

  • C5-H15-N2-O3-P-S.3H2-O

Molecular Weight

  • 268.2689
 

Classification Codes

  • Protectant (Topical)
  • Protective Agents
  • Radiation-Protective Agents
  • Radioprotector

Names and Synonyms

Name of Substance

  • Amifostine [USAN:USP:INN:BAN]

MeSH Heading

  • Amifostine

Synonyms

  • Amifostine
  • Amifostine trihydrate
  • Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
  • Ethyol
  • NSC 296961
  • S-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate, trihydrate
  • UNII-M487QF2F4V
  • WR 2721
  • WR-2721

Systematic Name

  • Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate

Registry Numbers

CAS Registry Number

  • 112901-68-5

FDA UNII

  • M487QF2F4V

System Generated Number

  • 0112901685

Molecular Formulas

Molecular Formula

  • C5-H15-N2-O3-P-S.3H2-O

Molecular Formula Fragments

  • C5-H15-N2-O3-P-S
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2

InChIKey

TXQPXJKRNHJWAX-UHFFFAOYSA-N

Smiles

C(CN)CNCCSP(=O)(O)O.O.O.O