|
|
|
Substance Name: Guanidine
RN: 113-00-8
UNII: JU58VJ6Y3B
InChIKey: ZRALSGWEFCBTJO-UHFFFAOYSA-N
Note
- A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Molecular Formula
- C-H5-N3
Molecular Weight
- 59.0715
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Code
- Natural Product
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Guanidine
MeSH Heading
- Guanidine
Synonyms
- 4-03-00-00148 (Beilstein Handbook Reference)
- Aminoformamidine
- Aminomethanamidine
- BRN 0506044
- Carbamamidine
- Carbamidine
- EINECS 204-021-8
- Guanidine
- HSDB 7603
- Imidourea
- Iminourea
- UNII-JU58VJ6Y3B
Systematic Name
- Guanidine
Registry Numbers
CAS Registry Number
- 113-00-8
FDA UNII
- JU58VJ6Y3B
Related Registry Numbers
- 1184-68-5 (unspecified sulfate)
- 1763-07-1 (unspecified phosphate)
- 19244-98-5 (mono-hydrobromide)
- 50-01-1 (mono-hydrochloride)
- 52470-25-4 (nitrate)
- 594-14-9 (sulfate 2:1)
- 64120-25-8 (monohydrate)
- 646-34-4 (sulfate 1:1)
System Generated Number
- 0000113008
Structure Descriptors
InChI
InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)InChIKey
ZRALSGWEFCBTJO-UHFFFAOYSA-NSmiles
NC(=N)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| frog | LDLo | subcutaneous | 3gm/kg (3000mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1352, 1935. | |
| mouse | LD50 | intraperitoneal | 350mg/kg (350mg/kg) | Bulletin of Experimental Biology and Medicine Vol. 61, Pg. 291, 1966. | |
| mouse | LDLo | subcutaneous | 266mg/kg (266mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1352, 1935. | |
| rabbit | LDLo | oral | 500mg/kg (500mg/kg) | "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 718, 1989. | |
| rat | LDLo | subcutaneous | 150mg/kg (150mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1352, 1935. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 50 | deg C | EXP | |
| log P (octanol-water) | -1.630 | (none) | EST | |
| Water Solubility | 1840 | mg/L | 20 | EXP |
| Vapor Pressure | 4.100 | mm Hg | 25 | EST |
| Henry's Law Constant | 2.34E-11 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 4.20E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.