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Substance Name: Argipressin [INN:BAN]
RN: 113-79-1
UNII: Y4907O6MFD
InChIKey: KBZOIRJILGZLEJ-LGYYRGKSSA-N

Note

  • The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked CYSTEINES at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Molecular Formula

  • C46-H65-N15-O12-S2

Molecular Weight

  • 1084.2445
 

Classification Codes

  • Antidiuretic
  • Antidiuretic Agents
  • Cardiovascular Agents
  • Coagulants
  • Hematologic Agents
  • Hemostatics
  • Hormone (Antidiuretic)
  • Natriuretic Agents
  • Vasoconstrictor Agents
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Names and Synonyms

Name of Substance

  • Argipressin
  • Argipressin [INN:BAN]
  • Argipressin [INN]

MeSH Heading

  • Arginine vasopressin

Synonyms

  • 8-Arginine-vasopressin
  • Argipresina
  • Argipresina [INN-Spanish]
  • Argipressin
  • Argipressina
  • Argipressina [DCIT]
  • Argipressine
  • Argipressine [INN-French]
  • Argipressinum
  • Argipressinum [INN-Latin]
  • EINECS 204-035-4
  • Pitressin
  • UNII-Y4907O6MFD
  • Vasopressin
  • Vasopressin (arginine form)

Systematic Names

  • Argipressin
  • Vasopressin, 8-L-arginine-

Registry Numbers

CAS Registry Number

  • 113-79-1

FDA UNII

  • Y4907O6MFD

System Generated Number

  • 0000113791

Structure Descriptors

InChI

1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1

InChIKey

KBZOIRJILGZLEJ-LGYYRGKSSA-N

Smiles

c1ccc(cc1)C[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N2)Cc3ccc(cc3)O)N)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N