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Substance Name: Epoetin Alfa [USAN:INN:BAN:JAN]
RN: 113427-24-0

Note

  • A recombinant form of erthropoietin that contains the 165 amino acid erythropoietin sequence. It differs from other epoetins by its distinct glycosylation pattern.

Classification Codes

  • Anti-Anemic
  • Hematinic
  • Hematinics
  • Hematologic Agents

Molecular Formula

  • C809-H1301-N229-O240-S5

Molecular Weight

  • 18235.8699
 

Names and Synonyms

Name of Substance

  • Epoetin alfa
  • Epoetin Alfa [USAN:INN:BAN:JAN]

MeSH Heading

  • Epoetin alfa

Synonyms

  • Abseamed
  • Binocrit
  • DRG-0062
  • EPO
  • Epoetin alfa
  • Epoetin alpha
  • Epoetin-alpha (genetical recombination)
  • Epoetina alfa
  • Epoetina alfa [INN-Spanish]
  • Epoetine alfa
  • Epoetine alfa [INN-French]
  • Epoetinum alfa
  • Epoetinum alfa [INN-Latin]
  • Epogen
  • Epogen/procrit
  • Eprex
  • Erypo
  • Erythropoietin alfa
  • Erythropoietin-alfa
  • Erythropoietin-alfa, recombinant
  • HSDB 7584
  • HX 575
  • Procrit
  • r-HuEPO
  • RTECS KQ2226000

Systematic Name

  • 1-165-Erythropoietin (human clone lambdaHEPOFL13 protein moiety), glycoform alpha

Registry Numbers

CAS Registry Number

  • 113427-24-0

System Generated Number

  • 0113427240

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 20ku/kg (20000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.
mouse LD50 intravenous 1270ku/kg (1270000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.
mouse LD50 oral 20ku/kg (20000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.
mouse LD50 subcutaneous 20ku/kg (20000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.
rat LD50 intravenous 20ku/kg (20000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.
rat LD50 oral 20ku/kg (20000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.
rat LD50 subcutaneous 20ku/kg (20000iu/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990.