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Substance Name: AMG-151 free base
RN: 1138669-65-4
UNII: P8B61X2X2D
InChIKey: PCOMIRCNMMNOAP-CQSZACIVSA-N

Note

  • A glucokinase activator.

Molecular Formula

  • C20-H18-N6-O3-S2

Molecular Weight

  • 454.5332
 
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Names and Synonyms

Name of Substance

  • AMG-151 free base

Synonyms

  • (1S)-1-(5-((3-((2-Methylpyridin-3-yl)oxy)-5-(pyridin-2-ylsulfanyl)pyridin-2-yl)amino)-1,2,4-thiadiazol-3-yl)ethane-1,2-diol
  • 1,2-Ethanediol, 1-(5-((3-((2-methyl-3-pyridinyl)oxy)-5-(2-pyridinylthio)-2-pyridinyl)amino)-1,2,4-thiadiazol-3-yl)-, (1S)-
  • AMG-151 free base
  • ARRY-403
  • UNII-P8B61X2X2D

Registry Numbers

CAS Registry Number

  • 1138669-65-4

FDA UNII

  • P8B61X2X2D

System Generated Number

  • 1138669654

Structure Descriptors

InChI

1S/C20H18N6O3S2/c1-12-15(5-4-8-21-12)29-16-9-13(30-17-6-2-3-7-22-17)10-23-19(16)25-20-24-18(26-31-20)14(28)11-27/h2-10,14,27-28H,11H2,1H3,(H,23,24,25,26)/t14-/m1/s1

InChIKey

PCOMIRCNMMNOAP-CQSZACIVSA-N

Smiles

Cc1ncccc1Oc2cc(Sc3ccccn3)cnc2Nc4nc(ns4)[C@H](O)CO