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Substance Name: Etilfelmin hydrochloride
RN: 1146-95-8
UNII: 01N5412224
InChIKey: NFYYMNADTASPEE-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H19-N.Cl-H

Molecular Weight

  • 273.805
 
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Names and Synonyms

Name of Substance

  • Etilfelmin hydrochloride

Synonyms

  • 2-Diphenylmethylenebutylamine hydrochloride
  • 2-Ethyl-3,3-diphenyl-2-propenylamine hydrochloride
  • EDPA hydrochloride
  • Ethyl-3,3-diphenyl-propen-yl-(2)-amin
  • Ethyl-3,3-diphenyl-propen-yl-(2)-amin [German]
  • Etifelmin hydrochloride
  • Etilfelmin HCl
  • Gilutensin
  • Tensinase D
  • UNII-01N5412224

Systematic Name

  • Butylamine, 2-diphenylmethylene-, hydrochloride

Registry Numbers

CAS Registry Number

  • 1146-95-8

FDA UNII

  • 01N5412224

Related Registry Number

  • 341-00-4 (Parent)

System Generated Number

  • 0001146958

Molecular Formulas

Molecular Formula

  • C17-H19-N.Cl-H

Molecular Formula Fragments

  • C17-H19-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H19N.ClH/c1-2-14(13-18)17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12H,2,13,18H2,1H3;1H

InChIKey

NFYYMNADTASPEE-UHFFFAOYSA-N

Smiles

NC\C(=C(/c1ccccc1)c1ccccc1)CC.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LD50 subcutaneous 58400ug/kg (58.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
guinea pig LD50 intraperitoneal 25mg/kg (25mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
guinea pig LD50 subcutaneous 33400ug/kg (33.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
mouse LD50 intraperitoneal 45500ug/kg (45.5mg/kg)   Drugs in Japan Vol. 6, Pg. 112, 1982.
mouse LD50 intravenous 28600ug/kg (28.6mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
mouse LD50 oral 115mg/kg (115mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
mouse LD50 subcutaneous 49400ug/kg (49.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
rabbit LD50 intravenous 20mg/kg (20mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
rat LD50 intraperitoneal 23400ug/kg (23.4mg/kg)   Drugs in Japan Vol. 6, Pg. 112, 1982.
rat LD50 intravenous 17400ug/kg (17.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
rat LD50 oral 148mg/kg (148mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.
rat LD50 subcutaneous 56400ug/kg (56.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 166, 1963.