Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Mephobarbital [USP:JAN]
RN: 115-38-8
UNII: 5NC67NU76B
InChIKey: ALARQZQTBTVLJV-UHFFFAOYSA-N

Note

  • A barbiturate that is metabolized to PHENOBARBITAL. It has been used for similar purposes, especially in EPILEPSY, but there is no evidence mephobarbital offers any advantage over PHENOBARBITAL.

Molecular Formula

  • C13-H14-N2-O3

Molecular Weight

  • 246.2646
 

Classification Codes

Classification Codes

  • Anticonvulsant
  • Anticonvulsants
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Drug / Therapeutic Agent
  • GABA Agents
  • GABA Modulators
  • Human Data
  • Hypnotics and Sedatives
  • Neurotransmitter Agents
  • Reproductive Effect
  • Sedative-Hypnotic

Superlist Classification Code

  • DEA Schedule IV
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Mephobarbital
  • Mephobarbital [USP:JAN]
  • Methylphenobarbital
  • Methylphenobarbital [INN]

MeSH Heading

  • Mephobarbital

Synonyms

  • 1-Methyl-5-ethyl-5-phenylbarbituric acid
  • 1-Methyl-5-phenyl-5-ethylbarbituric acid
  • 1-Methylphenobarbital
  • 5-24-09-00294 (Beilstein Handbook Reference)
  • 5-Ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
  • 5-Ethyl-1-methyl-5-phenylbarbituric acid
  • 5-Ethyl-5-phenyl-N-methyl-bartituric acid
  • 5-Ethyl-N-methyl-5-phenylbarbituric acid
  • 5-Phenyl-5-ethyl-3-methylbarbituric acid
  • BRN 0256144
  • EINECS 204-085-7
  • Enfenemal
  • Enphenemal
  • Enphenemalum
  • HSDB 3579
  • Isonal
  • Isonal (roussel)
  • Mebaral
  • Menta-Bal
  • Mephobarbital
  • Mephobarbitone
  • Mephytal
  • Methyl-calminal
  • Methylphenobarbital
  • Methylphenobarbitalum
  • Methylphenobarbitalum [INN-Latin]
  • Methylphenobarbitone
  • Methylphenobarbitonum
  • Methylphenolbarbital
  • Methylphenylbarbituric acid
  • Metilfenobarbital
  • Metilfenobarbital [INN-Spanish]
  • Metilfenobarbitale
  • Metilfenobarbitale [DCIT]
  • Metylfenemal
  • Metyna
  • Morbusan
  • N-Ethylmethylphenylbarbituric acid
  • N-Methyl-5-phenyl-5-ethylbarbital
  • N-Methylethylphenylbarbituric acid
  • N-Methylphenobarbital
  • N-Methylphenolbarbitol
  • Phemiton
  • Phemitone
  • Prominal
  • Prominaletten
  • Prominalum
  • UNII-5NC67NU76B

Systematic Names

  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-1-methyl-5-phenyl-
  • Barbituric acid, 5-ethyl-1-methyl-5-phenyl-
  • Methylphenobarbital

Superlist Names

  • DEA No. 2250
  • Mephobarbital
  • Methylphenobarbital

Mixture Name

  • Mebroin

Registry Numbers

CAS Registry Number

  • 115-38-8

FDA UNII

  • 5NC67NU76B

System Generated Number

  • 0000115388

Structure Descriptors

InChI

1S/C13H14N2O3/c1-3-13(9-7-5-4-6-8-9)10(16)14-12(18)15(2)11(13)17/h4-8H,3H2,1-2H3,(H,14,16,18)

InChIKey

ALARQZQTBTVLJV-UHFFFAOYSA-N

Smiles

CCC1(C(=O)NC(=O)N(C1=O)C)c2ccccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 230mg/kg (230mg/kg)   Drugs in Japan Vol. 6, Pg. 851, 1982.
mouse LD50 oral 300mg/kg (300mg/kg)   Helvetica Physiologia et Pharmacologica Acta. Vol. 19, Pg. 241, 1961.
rabbit LD50 oral 400mg/kg (400mg/kg)   Drugs in Japan Vol. 6, Pg. 851, 1982.
rat LD50 intraperitoneal 130mg/kg (130mg/kg) BEHAVIORAL: ANTICONVULSANT Pharmacologist. Vol. 5, Pg. 237, 1963.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 176 deg C   EXP
log P (octanol-water) 1.84 (none)   EXP
Water Solubility 666 mg/L 25 EST
Vapor Pressure 9.09E-12 mm Hg 25 EST
Henry's Law Constant 3.63E-14 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.07E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.