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Substance Name: Triphenyl phosphate
RN: 115-86-6
UNII: YZE19Z66EA
InChIKey: XZZNDPSIHUTMOC-UHFFFAOYSA-N

Molecular Formula

  • C18-H15-O4-P

Molecular Weight

  • 326.2865
 

Classification Codes

Classification Code

  • TSCA Flag TP (Subject to the Proposed TSCA Section 4 Test Rule)

Superlist Classification Codes

  • TWA 3 mg/m3
  • TWA 3 mg/m3; Not classifiable as a human carcinogen

Names and Synonyms

Name of Substance

  • Triphenyl phosphate

Synonyms

  • 4-06-00-00720 (Beilstein Handbook Reference)
  • AI3-04491
  • BRN 1888236
  • CCRIS 4888
  • Celluflex TPP
  • Disflamoll TP
  • EC 204-112-2
  • EINECS 204-112-2
  • HSDB 2536
  • NSC 57868
  • Phenyl phosphate ((PhO)3PO)
  • Phosflex TPP
  • Phosphoric acid, triphenyl ester
  • TP (VAN)
  • TPP
  • Trifenylfosfat
  • Trifenylfosfat [Czech]
  • Triphenoxyphosphine oxide
  • Triphenyl phosphate
  • Triphenylphosphate
  • UNII-YZE19Z66EA

Systematic Names

  • Phosphoric acid, triphenyl ester
  • Triphenyl phosphate

Superlist Names

  • Phosphoric acid, triphenyl ester
  • Triphenyl phosphate

Registry Numbers

CAS Registry Number

  • 115-86-6

FDA UNII

  • YZE19Z66EA

Other Registry Number

  • 402955-02-6

System Generated Number

  • 0000115866

Structure Descriptors

InChI

1S/C18H15O4P/c19-23(20-16-10-4-1-5-11-16,21-17-12-6-2-7-13-17)22-18-14-8-3-9-15-18/h1-15H

InChIKey

XZZNDPSIHUTMOC-UHFFFAOYSA-N

Smiles

P(Oc1ccccc1)(Oc1ccccc1)(Oc1ccccc1)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD intraperitoneal > 400mg/kg (400mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
cat LDLo oral 2gm/kg (2000mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 585, 1957.
cat LDLo subcutaneous 300mg/kg (300mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: TREMOR
National Institutes of Health, Bulletin. Vol. 160, Pg. 1, 1932.
chicken LDLo oral 5gm/kg (5000mg/kg) SPINAL CORD: OTHER DEGENERATIVE CHANGES National Technical Information Service. Vol. OTS0539872,
guinea pig LD oral > 4gm/kg (4000mg/kg)   Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
guinea pig LD subcutaneous > 3gm/kg (3000mg/kg)   Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
guinea pig LD50 skin > 4gm/kg (4000mg/kg)   Kodak Company Reports. Vol. 21MAY1971,
mammal (species unspecified) LC50 inhalation 4200mg/m3 (4200mg/m3) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(8), Pg. 98, 1974.
monkey LDLo subcutaneous 500mg/kg (500mg/kg)   The Threshold Limit Values Vol. 4, Pg. 420, 1980.
mouse LD subcutaneous > 3gm/kg (3000mg/kg)   Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
mouse LD50 intraperitoneal 1273mg/kg (1273mg/kg)   Agricultural and Biological Chemistry. Vol. 31, Pg. 1288, 1967.
mouse LD50 oral 1320mg/kg (1320mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(8), Pg. 98, 1974.
rabbit LD intramuscular > 1gm/kg (1000mg/kg)   National Institutes of Health, Bulletin. Vol. 160, Pg. 1, 1932.
rabbit LD50 skin > 7900mg/kg (7900mg/kg)   Toxicology and Applied Pharmacology. Vol. 41, Pg. 291, 1977.
rabbit LDLo oral 3gm/kg (3000mg/kg)   Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
rabbit LDLo subcutaneous 1gm/kg (1000mg/kg)   Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
rat LD intraperitoneal > 5gm/kg (5000mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0535042,
rat LD subcutaneous > 3gm/kg (3000mg/kg)   Archives of Environmental Health. Vol. 1, Pg. 33, 1960.
rat LD50 oral 3500mg/kg (3500mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA

BEHAVIORAL: TREMOR
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 585, 1957.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 50.5 deg C   EXP
log P (octanol-water) 4.59 (none)   EXP
Water Solubility 1.9 mg/L 25 EXP
Henry's Law Constant 3.31E-06 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.14E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.