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Substance Name: Tezacaftor [USAN]
RN: 1152311-62-0
UNII: 8RW88Y506K
InChIKey: MJUVRTYWUMPBTR-MRXNPFEDSA-N
Note
- A cystic fibrosis transmembrane conductance regulator (CFTR) modulator that enhances activity of CFTR mutants.
Molecular Formula
- C26-H27-F3-N2-O6
Molecular Weight
- 520.5013
Classification Code
- Treatment of Cystic Fibrosis
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Names and Synonyms
Name of Substance
- Tezacaftor [USAN]
Synonyms
- 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)cyclopropanecarboxamide
- Tezacaftor
- UNII-8RW88Y506K
- VX 661
- VX-661
Systematic Name
- Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)-
Registry Numbers
CAS Registry Number
- 1152311-62-0
FDA UNII
- 8RW88Y506K
System Generated Number
- 1152311620