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Substance Name: Dofetilide [USAN:USP:INN:BAN]
RN: 115256-11-6
UNII: R4Z9X1N2ND
InChIKey: IXTMWRCNAAVVAI-UHFFFAOYSA-N

Note

  • Potassium channel antagonist that has class III activity.

Molecular Formula

  • C19-H27-N3-O5-S2

Molecular Weight

  • 441.5703
 

Classification Codes

  • Anti-Arrhythmia Agents
  • Cardiac Depressant (Anti-Arrhythmic)
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Membrane Transport Modulators
  • Potassium Channel Blockers
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Dofetilide
  • Dofetilide [USAN:USP:INN:BAN]

Synonyms

  • beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide
  • Dofetilida
  • Dofetilida [INN-Spanish]
  • Dofetilide
  • Dofetilidum
  • Dofetilidum [INN-Latin]
  • HSDB 7927
  • Tikosyn
  • UK 68,798
  • UK 68798
  • UK-68,798
  • UNII-R4Z9X1N2ND

Systematic Name

  • Methanesulfonamide, N-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)ethyl)amino)ethyl)phenyl)-

Registry Numbers

CAS Registry Number

  • 115256-11-6

FDA UNII

  • R4Z9X1N2ND

System Generated Number

  • 0115256116

Structure Descriptors

InChI

InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3

InChIKey

IXTMWRCNAAVVAI-UHFFFAOYSA-N

Smiles

CN(CCOc1ccc(NS(=O)(=O)C)cc1)CCc2ccc(NS(=O)(=O)C)cc2