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Substance Name: Plazomicin [USAN:INN]
RN: 1154757-24-0
UNII: LYO9XZ250J
InChIKey: IYDYFVUFSPQPPV-PEXOCOHZSA-N

Classification Code

  • Treatment of Gram-Negative Bacterial Infections

Molecular Formula

  • C25-H48-N6-O10

Molecular Weight

  • 592.6862
 
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Names and Synonyms

Results Name

  • Plazomicin [USAN:INN]

Name of Substance

  • 6'-(Hydroxylethyl)-1-(haba)-sisomicin
  • Plazomicin [USAN:INN]

Synonyms

  • (2S)-4-Amino-N-((1R,2S,3S,4R,5S)-5-amino-4-((2-amino-2,3,4,6-tetradeoxy-6-((2- hydroxyethyl)amino)-alpha-D-glycero-hex-4-enopyranosyl)oxy)-2-((3-deoxy-4-C-methyl-3- (methylamino)-beta-L-arabinopyranosyl)oxy)-3-hydroxycyclohexyl)-2-hydroxybutanamide
  • 6'-(Hydroxylethyl)-1-(haba)-sisomicin
  • ACHN-490
  • Plazomicin
  • UNII-LYO9XZ250J

Systematic Name

  • D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-((2-hydroxyethyl)amino)-alpha-D-glycero- hex-4-enopyranosyl-(1->4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L- arabinopyranosyl-(1->6))-N(sup 1)-((2S)-4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-

Registry Numbers

CAS Registry Number

  • 1154757-24-0

FDA UNII

  • LYO9XZ250J

System Generated Number

  • 1154757240

Structure Descriptors

InChI

1S/C25H48N6O10/c1-25(37)11-38-24(18(35)21(25)29-2)41-20-15(31-22(36)16(33)5-6-26)9-14(28)19(17(20)34)40-23-13(27)4-3-12(39-23)10-30-7-8-32/h3,13-21,23-24,29-30,32-35,37H,4-11,26-28H2,1-2H3,(H,31,36)/t13-,14+,15-,16+,17+,18-,19-,20+,21-,23-,24-,25+/m1/s1

InChIKey

IYDYFVUFSPQPPV-PEXOCOHZSA-N

Smiles

CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3OC(=CC[C@H]3N)CNCCO)[C@@H](N)C[C@H]2NC(=O)[C@@H](O)CCN)OC[C@]1(C)O