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Substance Name: Zolamine hydrochloride [USAN]
RN: 1155-03-9
UNII: C2B9CF1640
InChIKey: GSDXPNOJFAITBE-UHFFFAOYSA-N

Classification Codes

  • Anesthetic (Topical)
  • Antihistaminic
  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H21-N3-O-S.Cl-H

Molecular Weight

  • 327.878
 
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Names and Synonyms

Name of Substance

  • Zolamine hydrochloride
  • Zolamine hydrochloride [USAN]

Synonyms

  • 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-thiazolyl-, HCl
  • 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-thiazolyl-, monohydrochloride
  • 194-B
  • 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)thiazole hydrochloride
  • 2-((2-(Dimethylamino)ethyl)-(p-methoxybenzyl)amino)thiazole monohydrochloride
  • N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2-thiazolyl)-ethylenediamine monohydrochloride
  • UNII-C2B9CF1640
  • Wl 291
  • WL-291
  • Zolamine HCl
  • Zolamine hydrochloride

Systematic Names

  • 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-thiazolyl-, monohydrochloride
  • Thiazole, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-, hydrochloride

Mixture Name

  • Otodyne

Registry Numbers

CAS Registry Number

  • 1155-03-9

FDA UNII

  • C2B9CF1640

System Generated Number

  • 0001155039

Molecular Formulas

Molecular Formula

  • C15-H21-N3-O-S.Cl-H

Molecular Formula Fragments

  • C15-H21-N3-O-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C15H21N3OS.ClH/c1-17(2)9-10-18(15-16-8-11-20-15)12-13-4-6-14(19-3)7-5-13;/h4-8,11H,9-10,12H2,1-3H3;1H

InChIKey

GSDXPNOJFAITBE-UHFFFAOYSA-N

Smiles

N(c1nccs1)(Cc1ccc(OC)cc1)CCN(C)C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 40mg/kg (40mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LDLo subcutaneous 140mg/kg (140mg/kg)   Compilation of LD50 Values of New Drugs.
rat LDLo oral 570mg/kg (570mg/kg)   Compilation of LD50 Values of New Drugs.
rat LDLo subcutaneous 275mg/kg (275mg/kg)   Compilation of LD50 Values of New Drugs.