Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Sulfapyrazine
RN: 116-44-9
UNII: 8BE3C727OG
InChIKey: YEAICDDXRUOCKJ-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C10-H10-N4-O2-S

Molecular Weight

  • 250.281
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Sulfapyrazine

Synonyms

  • 2-Sulfanilamidopyrazine
  • 4-Amino-N-pyrazinylbenzenesulfonamide
  • 5-25-10-00140 (Beilstein Handbook Reference)
  • BRN 0235481
  • N(sup 1)-2-Pyrazinylsulfonilamide
  • N1-2-Pyrazinylsulfanilamide
  • NSC 25872
  • NSC 41835
  • Pyrazine, sulfanilamido-
  • Sulfanilamide, N(sup 1)-(pyrazinyl)-
  • Sulfapyrazine
  • UNII-8BE3C727OG

Systematic Names

  • Benzenesulfonamide, 4-amino-N-pyrazinyl-
  • Sulfanilamide, N1-(pyrazinyl)- (8CI)

Registry Numbers

CAS Registry Number

  • 116-44-9

FDA UNII

  • 8BE3C727OG

System Generated Number

  • 0000116449

Structure Descriptors

InChI

1S/C10H10N4O2S/c11-8-1-3-9(4-2-8)17(15,16)14-10-7-12-5-6-13-10/h1-7H,11H2,(H,13,14)

InChIKey

YEAICDDXRUOCKJ-UHFFFAOYSA-N

Smiles

c1cc(ccc1N)S(=O)(=O)Nc2cnccn2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 5gm/kg (5000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 354, 1943.
mouse LD oral > 10gm/kg (10000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 354, 1943.
rat LD oral > 10gm/kg (10000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 354, 1943.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 251 deg C   EXP
log P (octanol-water) -0.340 (none)   EST
Water Solubility 50 mg/L 37 EXP
Atmospheric OH Rate Constant 2.80E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.