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Substance Name: Lanperisone hydrochloride
RN: 116287-13-9
UNII: JRF22NV56M
InChIKey: PHBZFPOOJUGYCR-RFVHGSKJSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H18-F3-N-O.Cl-H

Molecular Weight

  • 321.768
 
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Names and Synonyms

Name of Substance

  • Lanperisone hydrochloride

Synonyms

  • (-)-(R)-2-Methyl-3-(1-pyrrolidinyl)-4'-trifluoromethylpropiophenone monohydrochloride
  • (R)-2-Methyl-3-(1-pyrrolidinyl)-1-(4-(trifluoromethyl)phenyl)-1-propanone hydrochloride
  • 2-Methyl-3-(1-pyrrolidinyl)-4'-trifluoromethylpropiophenone monohydrochloride
  • Lanperisone hydrochloride
  • NK433
  • NK433 hydrochloride
  • UNII-JRF22NV56M

Systematic Name

  • 1-Propanone, 2-methyl-3-(1-pyrrolidinyl)-1-(4-(trifluoromethyl)phenyl)-, hydrochloride, (R)-

Registry Numbers

CAS Registry Number

  • 116287-13-9

FDA UNII

  • JRF22NV56M

System Generated Number

  • 0116287139

Molecular Formulas

Molecular Formula

  • C15-H18-F3-N-O.Cl-H

Molecular Formula Fragments

  • C15-H18-F3-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C15H18F3NO.ClH/c1-11(10-19-8-2-3-9-19)14(20)12-4-6-13(7-5-12)15(16,17)18;/h4-7,11H,2-3,8-10H2,1H3;1H/t11-;/m1./s1

InChIKey

PHBZFPOOJUGYCR-RFVHGSKJSA-N

Smiles

C([C@@H](CN1CCCC1)C)(=O)c1ccc(cc1)C(F)(F)F.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intravenous 49mg/kg (49mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 461, 1995.
rat LD50 oral 525mg/kg (525mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 461, 1995.