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Substance Name: Polyoxypropylene diepoxide 1000
RN: 116637-54-8

Classification Code

  • Drug / Therapeutic Agent
 
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Names and Synonyms

Synonym

  • De 1000

Systematic Name

  • Polyoxypropylene diepoxide 1000

Registry Numbers

CAS Registry Number

  • 116637-54-8

System Generated Number

  • 0116637548

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 193mg/kg (193mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (9-10), Pg. 42, 1993.
mammal (species unspecified) LC50 inhalation 38500mg/m3 (38500mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 28, 1987.
mammal (species unspecified) LD50 oral 6600mg/kg (6600mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 28, 1987.
mouse LC50 inhalation 38500mg/m3 (38500mg/m3)   Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (9-10), Pg. 42, 1993.
mouse LD50 oral 7450mg/kg (7450mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (9-10), Pg. 42, 1993.
rat LC50 inhalation 8310mg/m3 (8310mg/m3)   Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (9-10), Pg. 42, 1993.
rat LD50 oral 6644mg/kg (6644mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (9-10), Pg. 42, 1993.