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Substance Name: Bis(2-ethylhexyl)phthalate
RN: 117-81-7
UNII: C42K0PH13C
InChIKey: BJQHLKABXJIVAM-UHFFFAOYSA-N

Note

  • An ester of phthalic acid. It appears as a light-colored, odorless liquid and is used as a plasticizer for many resins and elastomers.

Molecular Formula

  • C24-H38-O4

Molecular Weight

  • 390.5602
 

Classification Codes

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Human Data
  • Mutation Data
  • Plasticizers
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 76
  • 2011 CERCLA Priority List, Rank: 76
  • Overall Carcinogenic Evaluation: Group 3
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 100 lb
  • TWA 5 mg/m3
  • TWA 5 mg/m3; Confirmed animal carcinogen with unknown relevance to humans

Names and Synonyms

Name of Substance

  • Bis(2-ethylhexyl) phthalate
  • Bis(2-ethylhexyl)phthalate
  • Di(2-ethylhexyl)phthalate
  • Diethylhexyl phthalate

MeSH Heading

  • Diethylhexyl phthalate

Synonyms

  • 4-09-00-03181 (Beilstein Handbook Reference)
  • AI3-04273
  • Bis(2-ethylhexyl) 1,2-benzenedicarboxylate
  • Bis(2-ethylhexyl) phthalate
  • Bis-(2-ethylhexyl)ester kyseliny ftalove
  • Bis-(2-ethylhexyl)ester kyseliny ftalove [Czech]
  • Bisoflex 81
  • Bisoflex DOP
  • BRN 1890696
  • Caswell No. 392K
  • CCRIS 237
  • Celluflex DOP
  • Compound 889
  • DEHP
  • Di(2-ethylhexyl) orthophthalate
  • Di(2-ethylhexyl) phthalate
  • Di(2-ethylhexyl)orthophthalate
  • Di(2-ethylhexyl)phthalate
  • Diacizer DOP
  • Diethylhexyl phthalate
  • Dioctyl phthalate
  • DOF
  • DOF [Russian plasticizer]
  • EC 204-211-0
  • EINECS 204-211-0
  • EPA Pesticide Chemical Code 295200
  • Ergoplast FDO
  • Ergoplast FDO-S
  • Etalon
  • Etalon (plasticizer)
  • Ethylhexyl phthalate
  • Eviplast 80
  • Eviplast 81
  • Fleximel
  • Flexol DOP
  • Flexol Plasticizer DOP
  • Good-rite GP 264
  • Hatcol DOP
  • Hercoflex 260
  • HSDB 339
  • Jayflex DOP
  • Kodaflex DEHP
  • Kodaflex DOP
  • Mollan O
  • Monocizer DOP
  • NCI-C52733
  • NSC 17069
  • Nuoplaz DOP
  • Octoil
  • Palatinol AH
  • Pittsburgh PX-138
  • Plasthall DOP
  • Platinol AH
  • Platinol DOP
  • PX-138
  • RC Plasticizer DOP
  • RCRA waste number U028
  • Reomol D 79P
  • Reomol DOP
  • Sansocizer DOP
  • Sansocizer R 8000
  • Sconamoll DOP
  • Sicol 150
  • Staflex DOP
  • Truflex DOP
  • UNII-C42K0PH13C
  • Vestinol AH
  • Vinicizer 80
  • Witcizer 312

Systematic Names

  • 1,2-Benzenedicarboxylic acid, 1,2-bis(2-ethylhexyl) ester
  • 1,2-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester
  • Bis(2-ethylhexyl) phthalate
  • Di(2-ethylhexyl) phthalate
  • Phthalic acid, bis(2-ethylhexyl) ester

Superlist Names

  • 1,2-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester
  • Bis(2-ethylhexyl) phthalate
  • DEHP
  • Di(2-ethylhexyl) phthalate
  • Di-(2-ethylhexyl) phthalate
  • Di-2-ethylhexyl phthalate
  • Di-2-ethylhexylphthalate
  • Di-sec-octyl phthalate
  • Diethylhexyl phthalate
  • Ethyl hexyl phthalate
  • Octyl phthalate
  • Phthalic acid, bis(2-ethylhexyl) ester
  • RCRA waste no. U028

Registry Numbers

CAS Registry Number

  • 117-81-7

FDA UNII

  • C42K0PH13C

Other Registry Numbers

  • 109630-52-6
  • 126639-29-0
  • 137718-37-7
  • 205180-59-2
  • 275818-89-8
  • 40120-69-2
  • 50885-87-5
  • 607374-50-5
  • 8033-53-2

System Generated Number

  • 0000117817

Structure Descriptors

InChI

1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3

InChIKey

BJQHLKABXJIVAM-UHFFFAOYSA-N

Smiles

CCCCC(CC)COC(=O)c1ccccc1C(=O)OCC(CC)CCCC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 26gm/kg (26000mg/kg)   IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 29, Pg. 269, 1982.
guinea pig LD50 skin 10gm/kg (10000mg/kg)   EHP, Environmental Health Perspectives. Vol. 4, Pg. 3, 1973.
guinea pig LD50 unreported 40500mg/kg (40500mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(7), Pg. 52, 1988.
man TDLo oral 143mg/kg (143mg/kg) GASTROINTESTINAL: OTHER CHANGES Journal of Industrial Hygiene and Toxicology. Vol. 27, Pg. 130, 1945.
mouse LD50 intraperitoneal 14gm/kg (14000mg/kg) BEHAVIORAL: EXCITEMENT

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
Journal of Pharmaceutical Sciences. Vol. 55, Pg. 158, 1966.
mouse LD50 intravenous 1060mg/kg (1060mg/kg)   National Technical Information Service. Vol. PB250-102,
mouse LD50 oral 1500mg/kg (1500mg/kg) GASTROINTESTINAL: NECROTIC GHANGES

LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 2, Pg. 59, 1961.
mouse LD50 unreported 7gm/kg (7000mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(7), Pg. 52, 1988.
mouse LDLo skin 4gm/kg (4000mg/kg) SKIN AND APPENDAGES (SKIN): OTHER GLANDS: OTHER Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(6), Pg. 35, 1980.
rabbit LD intraperitoneal > 31mL/kg (31mL/kg)   AMA Archives of Industrial Health. Vol. 13, Pg. 259, 1956.
rabbit LD50 oral 34gm/kg (34000mg/kg)   EHP, Environmental Health Perspectives. Vol. 4, Pg. 3, 1973.
rabbit LD50 skin 25gm/kg (25000mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 27, Pg. 130, 1945.
rat LD50 intraperitoneal 30700mg/kg (30700mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 27, Pg. 130, 1945.
rat LD50 intravenous 250mg/kg (250mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 45, Pg. 230, 1978.
rat LD50 oral 30gm/kg (30000mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 2, Pg. 32, 1975.
rat LD50 unreported 47gm/kg (47000mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(7), Pg. 52, 1988.
rat LDLo intratracheal 30mg/kg (30mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI

BLOOD: HEMORRHAGE
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 2, Pg. 59, 1961.
rat LDLo skin 4gm/kg (4000mg/kg) SKIN AND APPENDAGES (SKIN): OTHER GLANDS: OTHER Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(6), Pg. 35, 1980.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -5.50E+01 deg C   EXP
Boiling Point 384 deg C   EXP
log P (octanol-water) 7.6 (none)   EXP
Water Solubility 0.27 mg/L 25 EXP
Vapor Pressure 1.42E-07 mm Hg 25 EXP
Henry's Law Constant 2.70E-07 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.20E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.