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Substance Name: AMG-337
RN: 1173699-31-4
UNII: 08WG8S0L8D
InChIKey: DWHXUGDWKAIASB-CQSZACIVSA-N

Note

  • A mesenchymal epithelial transition factor inhibitor with antineoplastic activity.

Molecular Formula

  • C23-H22-F-N7-O3

Molecular Weight

  • 463.4708
 
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Names and Synonyms

Name of Substance

  • AMG-337

Synonyms

  • 1,6-Naphthyridin-5(6H)-one, 6-((1R)-1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo(4,3-a)pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-
  • AMG 337 [WHO-DD]
  • AMG-337
  • UNII-08WG8S0L8D

Registry Numbers

CAS Registry Number

  • 1173699-31-4

FDA UNII

  • 08WG8S0L8D

System Generated Number

  • 1173699314

Structure Descriptors

InChI

1S/C23H22FN7O3/c1-14(30-5-4-20-18(23(30)32)9-17(11-25-20)34-7-6-33-3)21-27-28-22-19(24)8-15(13-31(21)22)16-10-26-29(2)12-16/h4-5,8-14H,6-7H2,1-3H3/t14-/m1/s1

InChIKey

DWHXUGDWKAIASB-CQSZACIVSA-N

Smiles

COCCOc1cnc2C=CN([C@H](C)c3nnc4c(F)cc(cn34)c5cnn(C)c5)C(=O)c2c1