Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Cefditoren Pivoxil [JAN]
RN: 117467-28-4
UNII: 78THA212DH
InChIKey: AFZFFLVORLEPPO-UVYJNCLZSA-N

Note

  • ME 1207 is the pivaloyloxymethyl ester of ME 1206.

Molecular Formula

  • C25-H28-N6-O7-S3

Molecular Weight

  • 620.7292
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Anti-Infective Cephalosporin Antibiotic
  • Drug / Therapeutic Agent
  • Reproductive Effect

Names and Synonyms

Results Name

  • Cefditoren Pivoxil [JAN]

Name of Substance

  • Cefditoren pivaloyloxymethyl ester
  • Cefditoren pivoxil
  • Cefditoren pivoxil [USAN:JAN]

Synonyms

  • CCRIS 7768
  • CDTR-PI
  • Cefditoren PI voxil
  • Cefditoren pivoxil
  • Cefditorin
  • ME 1207
  • ME1207
  • Meiact
  • Spectracef
  • UNII-78THA212DH

Systematic Names

  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((1Z)-2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-,2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R-(3(Z),6-alpha,7-beta-(Z)))-
  • Cefditoren pivoxil

Registry Numbers

CAS Registry Number

  • 117467-28-4

FDA UNII

  • 78THA212DH

System Generated Number

  • 0117467284

Structure Descriptors

InChI

1S/C25H28N6O7S3/c1-12-15(41-10-27-12)7-6-13-8-39-21-17(29-19(32)16(30-36-5)14-9-40-24(26)28-14)20(33)31(21)18(13)22(34)37-11-38-23(35)25(2,3)4/h6-7,9-10,17,21H,8,11H2,1-5H3,(H2,26,28)(H,29,32)/b7-6-,30-16-/t17-,21-/m1/s1

InChIKey

AFZFFLVORLEPPO-UVYJNCLZSA-N

Smiles

CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)\C=C/c3scnc3C)\c4csc(N)n4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 2gm/kg (2000mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES Chemotherapy Vol. 40(Suppl,
mouse LD50 intraperitoneal 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Chemotherapy Vol. 40(Suppl,
mouse LD50 oral > 5100mg/kg (5100mg/kg)   Chemotherapy Vol. 40(Suppl,
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 40(Suppl,
rat LD50 oral > 5100mg/kg (5100mg/kg)   Chemotherapy Vol. 40(Suppl,
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Chemotherapy Vol. 40(Suppl,
rat LDLo intraperitoneal 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Chemotherapy Vol. 40(Suppl,