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Substance Name: Ponezumab [USAN:INN]
RN: 1178862-65-1


  • Binds amyloid beta-peptide.

Molecular Formula

  • C6552-H10158-N1730-O2090-S52

Classification Code

  • Treatment of Alzheimer's Disease
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Names and Synonyms

Name of Substance

  • Ponezumab [USAN:INN]


  • Immunoglobulin G2, anti-(human amyloid beta A4 protein (Alzheimer disease amyloid protein, ABPP, APPI, preA4, protease nexin-II)); humanized mouse monoclonal PF-04360365 clone 9TL des-442-lysine(CH3107-K)-(325-serine(CH299A>S),326- serine(CH2100P>S))gamma2 heavy chain (130-219')-disulfide with humanized mouse monoclonal PF-04360365 clone 9TL kappa light chain, dimer (218-218'':219-219'':222- 222':225-225'')-tetrakisdisulfide
  • PF 04360365
  • PF-04360365
  • Ponezumab
  • RN-1219
  • UNII-1TG15H1XE9

Systematic Name

  • Immunoglobulin G2, anti-(human beta-amyloid) (human-mouse monoclonal PF-04360365 clone 9TL heavy chain), disulfide with human-mouse monoclonal PF-04360365 clone 9TL light chain, dimer

Registry Numbers

CAS Registry Number

  • 1178862-65-1


  • 1TG15H1XE9

System Generated Number

  • 1178862651