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Substance Name: Tazarotene [USAN:INN:BAN]
RN: 118292-40-3
UNII: 81BDR9Y8PS
InChIKey: OGQICQVSFDPSEI-UHFFFAOYSA-N
Note
- A topical acetylenic retinoid; a topical kerytolytic.
Molecular Formula
- C21-H21-N-O2-S
Molecular Weight
- 351.468
Classification Codes
- Dermatologic Agents
- Keratolytic
- Keratolytic Agents
- Noxae
- Teratogens
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Names and Synonyms
Name of Substance
- Tazarotene
- Tazarotene [USAN:INN:BAN]
Synonyms
- AGN 190168
- AGN-190168
- Avage
- Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
- Fabior
- Tazarotene
- Tazorac
- UNII-81BDR9Y8PS
- Zorac
Systematic Name
- 3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-, ethyl ester
Registry Numbers
CAS Registry Number
- 118292-40-3
FDA UNII
- 81BDR9Y8PS
System Generated Number
- 0118292403
Structure Descriptors
InChI
InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3InChIKey
OGQICQVSFDPSEI-UHFFFAOYSA-NSmiles
CCOC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD | oral | > 2gm/kg (2000mg/kg) | Journal of the American Academy of Dermatology. Vol. 37(Suppl), Pg. S25, 1997. |