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Substance Name: Tyrphostin A23
RN: 118409-57-7
UNII: RV0GCD31OJ
InChIKey: VTJXFTPMFYAJJU-UHFFFAOYSA-N

Note

  • Inhibits EGF-stimulated thymidine incorporation as well as EGF-stimulated receptor autophosphorylation & tyrosine phosphorylation & cell proliferation.

Molecular Formula

  • C10-H6-N2-O2

Molecular Weight

  • 186.169
 

Classification Codes

  • Antineoplastic Agents
  • Enzyme Inhibitors
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Names and Synonyms

Name of Substance

  • Tyrphostin A23

Synonyms

  • (3,4-Dihydroxybenzylidene)malononitrile
  • (3,4-Dihydroxyphenyl)methylene propanedinitrile
  • AG 18
  • RG 50810
  • RG-50810
  • Tyrphostin 23
  • Tyrphostin A23
  • Tyrphostin AG18
  • Tyrphostin RG50810
  • UNII-RV0GCD31OJ

Systematic Name

  • Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)-

Registry Numbers

CAS Registry Number

  • 118409-57-7

FDA UNII

  • RV0GCD31OJ

System Generated Number

  • 0118409577

Structure Descriptors

InChI

1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H

InChIKey

VTJXFTPMFYAJJU-UHFFFAOYSA-N

Smiles

c1cc(\C=C(\C#N)C#N)cc(O)c1O