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Substance Name: Tyrphostin 25
RN: 118409-58-8
InChIKey: YZOFLYUAQDJWKV-UHFFFAOYSA-N

Note

  • Inhibits zymosan-stimulated PGE2 & LTC4 production; did not have any effect on human synovial fluid phospholipase A2 activity in vitro or on cyclooxygenase activity in the intact macrophage; did affect 5-lipoxygenase activity.

Classification Codes

  • Antineoplastic Agents
  • Enzyme Inhibitors

Molecular Formula

  • C10-H6-N2-O3

Molecular Weight

  • 202.1684
 
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Names and Synonyms

Name of Substance

  • Tyrphostin 25

Synonyms

  • ((3,4,5-Trihydroxyphenyl)methylene)propanedinitrile
  • (3,4,5-Trihydroxybenzylidene)-malononitrile
  • NSC 676484
  • Tyrphostin A25
  • Tyrphostin-25

Systematic Name

  • Propanedinitrile, ((3,4,5-trihydroxyphenyl)methylene)-

Registry Numbers

CAS Registry Number

  • 118409-58-8

System Generated Number

  • 0118409588

Structure Descriptors

InChI

1S/C10H6N2O3/c11-4-7(5-12)1-6-2-8(13)10(15)9(14)3-6/h1-3,13-15H

InChIKey

YZOFLYUAQDJWKV-UHFFFAOYSA-N

Smiles

c1c(cc(c(c1O)O)O)C=C(C#N)C#N