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Substance Name: Tyrphostin 47
RN: 118409-60-2
InChIKey: ZGHQGWOETPXKLY-XVNBXDOJSA-N

Note

  • Inhibits protein-tyrosine kinase activity of EGF-R both in vitro and in living cells.

Classification Code

  • Enzyme Inhibitors

Molecular Formula

  • C10-H8-N2-O2-S

Molecular Weight

  • 220.251
 
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Names and Synonyms

Name of Substance

  • Tyrphostin 47

Synonyms

  • 2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenethioamide
  • 3,4-Dihydroxy-alpha-cyanothiocinnamide
  • 3,4-Dihydroxybenzylidenethioacetamide
  • AG 213
  • AG-213
  • alpha-Cyano-3,4-dihydroxythiocinnamamide
  • RG 50864
  • RG-50864
  • RG50864
  • Tyrphostin 47
  • Tyrphostin A47
  • Tyrphostin AG-213
  • Tyrphostin AG213
  • Tyrphostin RG50864

Systematic Name

  • 2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)-

Registry Numbers

CAS Registry Number

  • 118409-60-2

System Generated Number

  • 0118409602

Structure Descriptors

InChI

1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+

InChIKey

ZGHQGWOETPXKLY-XVNBXDOJSA-N

Smiles

c1cc(\C=C(/C#N)C(N)=S)cc(O)c1O