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Substance Name: Nebivolol [USAN:INN:BAN]
RN: 118457-14-0
UNII: 030Y90569U
InChIKey: KOHIRBRYDXPAMZ-YHBROIRLSA-N

Note

  • Selective b1-blocker with additional vasodilator effects which are mediated by the endothelial L-arginine/nitric oxide system.

Molecular Formula

  • C22-H25-F2-N-O4

Molecular Weight

  • 405.4385
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic Antagonists
  • Adrenergic beta-1 Receptor Antagonists
  • Adrenergic beta-Antagonists
  • Antihypertensive (beta-Blocker)
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Neurotransmitter Agents
  • Vasodilator Agents

Names and Synonyms

Name of Substance

  • Nebivolol
  • Nebivolol [USAN:INN:BAN]

Synonyms

  • (+-)-Nebivolol
  • Bystolic
  • dl-Nebivolol
  • Nebivolol
  • Nobiten
  • R 065824
  • R65,824
  • UNII-030Y90569U
  • Vasoxen

Systematic Name

  • 2H-1-Benzopyran-2-methanol, alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro-, (2R*(R*(R*(S*))))-

Registry Numbers

CAS Registry Number

  • 118457-14-0

FDA UNII

  • 030Y90569U

Other Registry Numbers

  • 129939-78-2
  • 599211-45-7

System Generated Number

  • 0118457140

Structure Descriptors

InChI

1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2/t17-,18-,21-,22+/m1/s1

InChIKey

KOHIRBRYDXPAMZ-YHBROIRLSA-N

Smiles

O[C@H](CNC[C@@H](O)[C@@H]1CCc2cc(F)ccc2O1)[C@H]3CCc4cc(F)ccc4O3