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Substance Name: Tromethamine hydrochloride
RN: 1185-53-1
UNII: 383V75M34E
InChIKey: QKNYBSVHEMOAJP-UHFFFAOYSA-N

Note

  • An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)

Molecular Formula

  • C4-H11-N-O3.Cl-H

Molecular Weight

  • 157.596
 
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Names and Synonyms

Name of Substance

  • Tromethamine hydrochloride

Synonyms

  • 2-Amino-2-hydroxymethyl-1,3-propanediol hydrochloride
  • EINECS 214-684-5
  • Tris chloride
  • Tris hydrochloride
  • Tris hydrochloride buffer
  • Tris(hydroxymethyl)aminomethane hydrochloride
  • Trizma hydrochloride
  • Tromethamine HCl
  • Tromethamine hydrochloride
  • UNII-383V75M34E

Systematic Names

  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1)
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride

Registry Numbers

CAS Registry Number

  • 1185-53-1

FDA UNII

  • 383V75M34E

Other Registry Numbers

  • 150551-82-9
  • 35087-75-3

System Generated Number

  • 0001185531

Molecular Formulas

Molecular Formula

  • C4-H11-N-O3.Cl-H

Molecular Formula Fragments

  • C4-H11-N-O3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChIKey

QKNYBSVHEMOAJP-UHFFFAOYSA-N

Smiles

C(C(N)(CO)CO)O.Cl