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Substance Name: Dalantercept [USAN:INN]
RN: 1186210-24-1


  • Derived from ALK1 and the Fc portion of IgG1.

Molecular Formula

  • C3206-H4960-N904-O976-S38 (peptide)

Classification Code

  • Antineoplastic
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Names and Synonyms

Name of Substance

  • Dalantercept [USAN:INN]


  • (Human serine/threonine-protein kinase receptor R3 (activin receptor-like kinase 1, TGF-B superfamily receptor type I, EC (containing extracellular domain))-threonyltriglycyl-(Ala115,Ala118,Val211,Pro284) human immunoglobulin heavy constant gamma 1Fc (C-terminal fragment 104-328) (H-(8-15)- CH24L>A,CH27G>A,CH2100A>V,CH363S>P), dimer (107-107':110-110')-bisdisulfide
  • ACE 041
  • ACE-041
  • AXCE 041
  • Dalantercept
  • UNII-EGC16R10V0

Systematic Name

  • Kinase (phosphorylating), activin receptor-like, 1 (human 99-amino acid extracellular domain fragment) fusion protein with peptide (synthetic 4-amino acid linker) fusion protein with immunoglobulin G1 (human 225-amino acid Fc region fragment), dimer

Registry Numbers

CAS Registry Number

  • 1186210-24-1


  • EGC16R10V0

System Generated Number

  • 1186210241