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Substance Name: Sarilumab [USAN:INN]
RN: 1189541-98-7


  • Antibody against IL-6Ralpha in patients with rheumatoid arthritis.

Molecular Formula

  • C6388-H9918-N1718-O1998-S44

Classification Codes

  • Antiviral (COVID-19)
  • Treatment of Rheumatoid Arthritis and Ankylosing Spondylitis
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Links to Resources

Names and Synonyms

Name of Substance

  • Sarilumab [USAN:INN]


  • Immunoglobulin G1, anti-(human interleukin-6 receptor subunit alpha (IL-6RA, membrane glycoprotein 80, CD126)); human monoclonal RGN88 gamma1 heavy chain (219- 214')-disulfide with human monoclonal RGN88 kappa light chain dimer (225-225'':228- 228'')-bisdisulfide
  • Kevzara
  • REGN 88
  • REGN-88
  • REGN88
  • SAR 153191
  • SAR-153191
  • SAR153191
  • Sarilumab
  • UNII-NU90V55F8I

Systematic Name

  • Immunoglobulin G1, anti-(human interleukin 6 receptor alpha) (human REGN88 heavy chain), disulfide with human REGN88 light chain, dimer

Registry Numbers

CAS Registry Number

  • 1189541-98-7


  • NU90V55F8I

System Generated Number

  • 1189541987