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Substance Name: Phentermine hydrochloride [USP]
RN: 1197-21-3
UNII: 0K2I505OTV
InChIKey: NCAIGTHBQTXTLR-UHFFFAOYSA-N

Note

  • A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.

Molecular Formula

  • C10-H15-N.Cl-H

Molecular Weight

  • 185.6964
 

Classification Codes

Classification Codes

  • Adrenergic Agents
  • Anti-Obesity Agents
  • Appetite Depressants
  • Appetite Suppressant (Systemic)
  • Autonomic Agents
  • Central Nervous System Agents
  • Central Nervous System Stimulants
  • Drug / Therapeutic Agent
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Sympathomimetics

Superlist Classification Code

  • DEA Schedule IV
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Names and Synonyms

Name of Substance

  • Phentermine hydrochloride [USP]

Synonyms

  • 1-Phenyl-2-methyl-2-aminopropane hydrochloride
  • Adipex-P
  • alpha,alpha-Dimethylphenethylamine hydrochloride
  • alpha-Methylamphetamine hydrochloride
  • Benzeneethanamine, alpha,alpha-dimethyl, hydrochloride
  • EINECS 214-821-9
  • Fastin
  • Ionamin
  • Lomaira
  • MG 18370
  • NSC 44090
  • Obestin-30
  • Oby-Trim
  • Ona-Mast
  • Ona-Mast hydrochloride
  • Phenteral
  • Phentermine HCl
  • Phentermine hydrochloride
  • Phentermyl Wyncaps
  • Phenyl-t-butylamine hydrochloride
  • S 58
  • Suprenza
  • Tora
  • UNII-0K2I505OTV
  • Wilpo (VAN)

Systematic Names

  • Benzeneethanamine, alpha,alpha-dimethyl-, hydrochloride
  • Phenethylamine, alpha,alpha-dimethyl-, hydrochloride
  • Phentermine hydrochloride

Superlist Names

  • Adipex-P
  • DEA No. 1640

Registry Numbers

CAS Registry Number

  • 1197-21-3

FDA UNII

  • 0K2I505OTV

Related Registry Number

  • 122-09-8 (Parent)

System Generated Number

  • 0001197213

Molecular Formulas

Molecular Formula

  • C10-H15-N.Cl-H

Molecular Formula Fragments

  • C10-H15-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C10H15N.ClH/c1-10(2,11)8-9-6-4-3-5-7-9;/h3-7H,8,11H2,1-2H3;1H

InChIKey

NCAIGTHBQTXTLR-UHFFFAOYSA-N

Smiles

Cl.CC(C)(N)Cc1ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 154mg/kg (154mg/kg)   Toxicology and Applied Pharmacology. Vol. 3, Pg. 256, 1961.
rabbit LD50 intravenous 15mg/kg (15mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 187, 1943.
rat LD50 intraperitoneal 81mg/kg (81mg/kg)   Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 121, 1960.
rat LD50 oral 188mg/kg (188mg/kg)   Toxicology and Applied Pharmacology. Vol. 3, Pg. 256, 1961.