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Substance Name: Chrysotile asbestos
RN: 12001-29-5
UNII: 8FDH1JN7VQ
InChIKey: CWBIFDGMOSWLRQ-UHFFFAOYSA-N

Note

  • A type of asbestos that occurs in nature as the dihydrate of magnesium silicate. It exists in two forms: antigorite, a plated variety, and chrysotile, a fibrous variety. The latter makes up 95% of all asbestos products. (From Merck Index, 11th ed, p.893)

Molecular Formula

  • H4-O4-Si.1/2H2-O.1/2Mg

Molecular Weight

  • 277.11
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Natural Product
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 119
  • 2011 CERCLA Priority List, Rank: 119
  • Known to be a Carcinogen
  • Overall Carcinogenic Evaluation: Group 1
  • TWA 0.1 mg/m3; (longer than 5 um); Confirmed human carcinogen
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Names and Synonyms

Name of Substance

  • Chrysotile asbestos

MeSH Heading

  • Asbestos, serpentine

Synonyms

  • 5R04
  • 5Ro4
  • 7-45 Asbestos
  • Asbestos (chrysotile)
  • Avibest C
  • Calidria RG 100
  • Calidria RG 144
  • Calidria RG 600
  • Cassiar AK
  • CCRIS 378
  • Chrysotile
  • Chrysotile (Mg3(OH)4(SiO5))
  • Chrysotile A
  • Chrysotile A asbestos
  • Chrysotile asbestos
  • Chrysotile uicc
  • Hooker No. 1 chrysotile asbestos
  • HSDB 2966
  • K 6-30
  • K6-30
  • Metaxite
  • NCI C61223A
  • Plastibest 20
  • RG 600
  • Serpentine
  • Serpentine chrysotile
  • Sylodex
  • UNII-8FDH1JN7VQ
  • White asbestos

Systematic Names

  • Asbestos, chrysotile
  • Chrysotile (Mg3H2(SiO4)2.H2O)
  • Chrysotile asbestos

Superlist Names

  • Asbestos, chrysotile
  • Chrysotile
  • Chrysotile asbestos
  • Chrysotile [Asbestos]
  • UN2590
  • White asbestos (chrysotile, actinolite, anthophyllite, tremolite)
  • White asbestos (chrysotile, actinolite, anthophyllite, tremolite) [UN2590] [Class 9]

Registry Numbers

CAS Registry Number

  • 12001-29-5

FDA UNII

  • 8FDH1JN7VQ

Other Registry Number

  • 61076-97-9

System Generated Number

  • 0012001295

Molecular Formulas

Molecular Formula

  • H4-O4-Si.1/2H2-O.1/2Mg

Molecular Formula Fragments

  • COMPONENT
  • H2-O
  • H4-O4-Si
  • Mg

Structure Descriptors

InChI

1S/3Mg.2HO4Si.H2O/c;;;2*1-5(2,3)4;/h;;;2*1H;1H2/q3*+2;2*-3;

InChIKey

CWBIFDGMOSWLRQ-UHFFFAOYSA-N

Smiles

[Si]([O-])(O)([O-])[O-].[Mg+2].O.[Si]([O-])(O)([O-])[O-].[Mg+2].[Mg+2]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TCLo inhalation 2.8fb/cc/5Y (2.8fb/cc) LUNGS, THORAX, OR RESPIRATION: "FIBROSIS, FOCAL (PNEUMOCONIOSIS)"

LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Environmental Research. Vol. 23, Pg. 292, 1980.
rat LDLo intraperitoneal 300mg/kg (300mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: PERITONITIS
American Journal of Pathology. Vol. 70, Pg. 291, 1973.