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Substance Name: Donepezil hydrochloride [USAN:USP]
RN: 120011-70-3
UNII: 3O2T2PJ89D
InChIKey: XWAIAVWHZJNZQQ-UHFFFAOYSA-N

Note

  • FDA approved for the treatment of mild to moderate dementia of the Alzheimer type.

Molecular Formula

  • C24-H29-N-O3.Cl-H

Molecular Weight

  • 415.958
 

Classification Codes

  • Alzheimer's Disease Treatment (Adjunct)
  • Cognition Adjuvant
  • Dementia Symptoms Treatment Adjunct
  • Inhibitor (Acetylcholinesterase)

Names and Synonyms

Name of Substance

  • Donepezil hydrochloride
  • Donepezil hydrochloride [USAN:USP]
  • E 2020

Synonyms

  • (+-)-2-((1-Benzyl-4-piperidyl)methyl)-5,6-dimethoxy-1-indanone hydrochloride
  • 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl
  • Aricept
  • Aricept ODT
  • BNAG
  • Donepezil HCl
  • Donepezil hydrochloride
  • E 2020 (pharmaceutical)
  • E-2020
  • E2020
  • UNII-3O2T2PJ89D

Systematic Name

  • 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 120011-70-3

FDA UNII

  • 3O2T2PJ89D

Other Registry Number

  • 142057-77-0

System Generated Number

  • 0120011703

Molecular Formulas

Molecular Formula

  • C24-H29-N-O3.Cl-H

Molecular Formula Fragments

  • C24-H29-N-O3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H

InChIKey

XWAIAVWHZJNZQQ-UHFFFAOYSA-N

Smiles

Cl.COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC