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Substance Name: Thrazarine
RN: 120128-14-5
InChIKey: WAKGSHQRLIGGLB-DMTCNVIQSA-N

Note

  • From Streptomyces coerulescens MH802-fF5.

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data

Molecular Formula

  • C7-H11-N3-O5

Molecular Weight

  • 217.18
 
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Names and Synonyms

Name of Substance

  • Thrazarine

Synonyms

  • O-((3R)-2-Diazo-3-hydroxybutyryl)-L-serine
  • Thrazarine

Systematic Name

  • L-Serine, 2-diazo-3-hydroxybutanoate (ester), (R)-

Registry Numbers

CAS Registry Number

  • 120128-14-5

System Generated Number

  • 0120128145

Structure Descriptors

InChI

1S/C7H11N3O5/c1-3(11)5(10-9)7(14)15-2-4(8)6(12)13/h3-4,11H,2,8H2,1H3,(H,12,13)/t3-,4+/m1/s1

InChIKey

WAKGSHQRLIGGLB-DMTCNVIQSA-N

Smiles

C([C@@H](N)COC(=O)C([C@@H](C)O)=[N+]=[N-])(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo intravenous 500mg/kg (500mg/kg)   Journal of Antibiotics. Vol. 41, Pg. 1561, 1988.