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Substance Name: Ammonium chloride [USP:JAN]
RN: 12125-02-9
UNII: 01Q9PC255D
InChIKey: NLXLAEXVIDQMFP-UHFFFAOYSA-N

Note

  • An acidifying agent that has expectorant and diuretic effects. Also used in etching and batteries and as a flux in electroplating.

Molecular Formulas

  • Cl-H4-N
  • N-H4-Cl

Molecular Weight

  • 53.4916
 

Classification Codes

Classification Codes

  • Acidifier
  • Diuretic
  • Drug / Therapeutic Agent
  • Human Data
  • Mutation Data
  • Skin / Eye Irritant

Superlist Classification Codes

  • Reportable Quantity (RQ) = 5000 lb
  • TWA 10 mg/m3; STEL 20 mg/m3

Names and Synonyms

Name of Substance

  • Ammonium chloride
  • Ammonium chloride [USP:JAN]
  • Ammonium muriate
  • Sal ammoniac

MeSH Heading

  • Ammonium chloride

Synonyms

  • AI3-08937
  • Amchlor
  • Ammon Chlor
  • Ammonchlor
  • Ammoneric
  • Ammonii Chloridum
  • Ammonium Chloratum
  • Ammonium chloride
  • Ammonium chloride ((NH4)Cl)
  • Ammonium chloride 0.9% in normal saline
  • Ammonium chloride 2.14%
  • Ammonium chloride in plastic container
  • Ammonium Chloride Injection
  • Ammonium Chloride Tablets
  • Ammonium muriate
  • Ammoniumchlorid
  • Ammoniumchlorid [German]
  • Ammoniumklorid
  • CCRIS 7262
  • Chlorammonic
  • Chlorammonic [France]
  • Chloramon
  • Chlorid ammonia
  • Chlorid ammonia [Czech]
  • Chlorid amonny
  • Chlorid amonny [Czech]
  • Cloruro de Amonio
  • Darammon
  • EC 235-186-4
  • EINECS 235-186-4
  • Elektrolyt
  • Gen-Diur (Spain)
  • HSDB 483
  • Muriate of Ammonia
  • Sal ammonia
  • Sal ammoniac
  • Salammonite
  • Salmiac
  • UNII-01Q9PC255D

Systematic Names

  • Ammonium chloride
  • Ammonium chloride ((NH4)Cl)

Superlist Names

  • Ammonium chloride
  • Ammonium chloride fume

Mixture Name

  • PV Tussin Syrup

Registry Numbers

CAS Registry Number

  • 12125-02-9

FDA UNII

  • 01Q9PC255D

Other Registry Numbers

  • 1260366-18-4
  • 127634-24-6
  • 128532-42-3
  • 154383-48-9
  • 15630-61-2
  • 20548-08-7
  • 50295-88-0
  • 55871-05-1
  • 75944-36-4
  • 867060-75-1
  • 89485-84-7
  • 89485-85-8

Related Registry Number

  • 54450-56-5 ((ammonium)HCl2))

System Generated Number

  • 0012125029

Structure Descriptors

InChI

1S/ClH.H3N/h1H;1H3

InChIKey

NLXLAEXVIDQMFP-UHFFFAOYSA-N

Smiles

[NH4+].[Cl-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 600mg/kg (600mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
domestic animals - goat/sheep LDLo oral 1500mg/kg (1500mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: TREMOR

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
American Journal of Veterinary Research. Vol. 32, Pg. 1229, 1971.
guinea pig LDLo intravenous 220mg/kg (220mg/kg)   "Handbuch der Experimentellen Pharmakologie," Heffter, A., Berlin, Verlag von Julius Springer. V.1-3, 1920-35. For publisher information, see HEPHD2.Vol. 1, Pg. 470, 1923.
guinea pig LDLo subcutaneous 72mg/kg (72mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
infant LDLo oral 2gm/kg (2000mg/kg) CARDIAC: OTHER CHANGES American Journal of Emergency Medicine. Vol. 6, Pg. 506, 1988.
mouse LD50 intraperitoneal 485mg/kg (485mg/kg)   Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
mouse LD50 intravenous 358mg/kg (358mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Clinical Investigation. Vol. 37, Pg. 497, 1958.
mouse LD50 oral 1300mg/kg (1300mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 257, 1990.
mouse LDLo subcutaneous 500mg/kg (500mg/kg)   "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 39, 1973.
rabbit LDLo intravenous 78mg/kg (78mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rabbit LDLo oral 1gm/kg (1000mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rabbit LDLo subcutaneous 200mg/kg (200mg/kg)   "Handbuch der Experimentellen Pharmakologie," Heffter, A., Berlin, Verlag von Julius Springer. V.1-3, 1920-35. For publisher information, see HEPHD2.Vol. 1, Pg. 470, 1923.
rat LD50 intramuscular 30mg/kg (30mg/kg)   Experimental Medicine and Surgery. Vol. 4, Pg. 223, 1946.
rat LD50 oral 1650mg/kg (1650mg/kg)   "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 15, 1972.
rat LD50 unreported 550mg/kg (550mg/kg)   French Demande Patent Document. Vol. #2444025,