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Substance Name: Pidotimod [INN]
RN: 121808-62-6
UNII: 785363R681
InChIKey: UUTKICFRNVKFRG-WDSKDSINSA-N

Classification Codes

  • Adjuvants, Immunologic
  • Drug / Therapeutic Agent
  • Immunologic Factors

Molecular Formula

  • C9-H12-N2-O4-S

Molecular Weight

  • 244.2698
 
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Names and Synonyms

Name of Substance

  • Pidotimod
  • Pidotimod [INN]

Synonyms

  • (R)-3-((S)-(5-Oxo-2-pyrrolidinyl)carbonyl)-thiazolidin-4-carbonsaeure
  • (R)-3-((S)-(5-Oxo-2-pyrrolidinyl)carbonyl)-thiazolidin-4-carbonsaeure [German]
  • (R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid
  • (R-(R*,S*))-3-((5-Oxo-2-pyrrolidinyl)carbonyl)-4-thiazolidinecarboxylic acid
  • BRN 6636310
  • CCRIS 7271
  • PGT/1A
  • Pidotimod
  • Pidotimodum
  • Pidotimodum [INN-Latin]
  • Pidotomod
  • UNII-785363R681

Systematic Names

  • (R)-3-((S)-5-Oxoprolyl)-4-thiazolidinecarboxylic acid
  • 4-Thiazolidinecarboxylic acid, 3-((5-oxo-2-pyrrolidinyl)carbonyl)-, (R-(R*,S*))-
  • Pidotimod

Registry Numbers

CAS Registry Number

  • 121808-62-6

FDA UNII

  • 785363R681

System Generated Number

  • 0121808626

Structure Descriptors

InChI

1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1

InChIKey

UUTKICFRNVKFRG-WDSKDSINSA-N

Smiles

C1[C@H](N(CS1)C([C@@H]1CCC(N1)=O)=O)C(O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intramuscular > 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
dog LD50 intravenous > 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
dog LD50 oral > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 intramuscular > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 intraperitoneal 3700mg/kg (3700mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 intravenous > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 oral > 8gm/kg (8000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 intramuscular > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 intraperitoneal 5800mg/kg (5800mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 intravenous > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 oral > 8gm/kg (8000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.